Good stuff! > Activation of Rev-ErbA-α by SR9009 in mice increases exercise capacity by increasing mitochondria counts in skeletal muscle. > Some companies ar

Good stuff! > Activation of Rev-ErbA-α by SR9009 in mice increases exercise capacity by increasing mitochondria counts in skeletal muscle. > Some companies are selling SR9009 online for human use as a 'research chemical'. > "The drug [alters] the circadian rhythm (in mice) and we would need to assume in humans – and we don't know if it is beneficial or detrimental at this point." --- It has "several issues that make it unsuitable for human use". > Firstly, it has no oral bioavailability. I know the company selling this is indicating taking it orally is ok – but it doesn't even get into the blood. > SR9009 has some functional groups that are known to have potential toxicology liabilities and it would never be developed as a drug. > So bottom line – I would never recommend using this compound at this point. That being said – we are still working on improved compounds with one of the potential uses being sarcopenia – loss of muscle and strength due to aging.