2 ms·
Not really in time. In principle, yes, but antibodies are more complicated than normal molecules (glycosylation, protein folding) so you can really only indust
by dnautics 7y ago
Not really in time.
In principle, yes, but antibodies are more complicated than normal molecules (glycosylation, protein folding) so you can really only industrially prepare them in certain types of cells (pretty much Chinese Hamster Ovary, last I checked).
Another problem is retrieving the correct antibody gene sequence. All immunoactive antibodies have been subjected to a process of internal evolution and artificial selection. Their DNA is not the same as your germline DNA, through shuffling and active mutation events, and indeed every immune cell that produces antibodies has different DNA than the other ones (that haven't been told to clone themselves) so it's really difficult to retrieve the correct gene sequence.
In practice I wouldn't estimate it to be possible to do this in the 4-6 month timeframe. Maybe in the 6-12 month timeframe under emergency duress situations.