5 ms·
Some emerging theories of pathology suggest that lung function can be increased by reinflating collapsed alveoli with constant pressure: https://emcrit.org/pulm
by tcbawo 7y ago
Some emerging theories of pathology suggest that lung function can be increased by reinflating collapsed alveoli with constant pressure: https://emcrit.org/pulmcrit/cpap-covid/ https://emcrit.org/pulmcrit/cpap-covid/. It describes cases where oxygen supplementation could be reduced or eliminated.
This development (https://www.isinnova.it/easy-covid19-eng/ https://www.isinnova.it/easy-covid19-eng/) looks very promising for 'sub-intensive' cases -- adapting decathlon mask/snorkel with a 3D printed valve to provide positive air pressure (to help reinflate lungs) without intubation or leaking contaminated exhaust. If the closed mask method could be used successfully to prevent serious cases from progressing to ICU (or more importantly, keep people in their homes a little longer), it could have a huge impact on reducing load in the hospital system.
- agumonkey 7y agoI don't know where to ask.. is vaporized cbd helpful ? it's said to be a potent anti inflammatory compounds and also help cleansing cells through apoptosis.
- DrAwdeOccarim 7y agoI doubt it, though I don't have any references. Do you have any peer reviewed papers on CBD and lung function?
- agumonkey 7y agoI'm not on my laptop but the are a few studies on cannabinoids and lung tissue. I'll edit this later
- jeltz 7y agoI am not a doctor but if it is indeed anti-inflammatory and causes apoptosis it sounds more likely to be harmful than to be helpful. I suspect apoptosis (or rather what happens is that cells get hijacked by the virus and then the immune systems kills the hijacked cells) is what causes most of the lung damage and inflammation is an important part of the response from the immune system so I would not mess with that more than necessary.
- agumonkey 7y agogood point, although reduce inflammation would clearly help respiratory distress.. I'll dig further
- deleted 7y ago[deleted]
- hhas01 7y agoExercise due caution with regard to CBD, megadose Vit C, “MMS” (aka industrial bleach), etc, etc. The people advancing these miracle claims are almost always either indulging, selling, or both. Ego and money corrupt even good science when we let them; imagine what they do in presence of unquestioning, evangelical Beliefs. And they are out in force right now, putting even the most venal pharma corp to shame. Panic is no reason to bypass robust replicated research, or even more will die. Best thing is not to catch COVID-19 in the first place. Next best is not to catch it all at once. And if you do catch it, follow the latest treatment guidelines and do your best not to pass it to anyone else. Be safe.
- agumonkey 7y agothis is unrelated to snake oil, also this was for people already infected to help SARS also most readings on the topic are from ncbi/pubmed or springer books
- hhas01 7y agoCBD is interesting but regularly overhyped; lots of “believed” and “may”, personal testimonials and pilot trials; not a lot of robust large-scale trials to really sift out the truth. PubMed is just an index of published research, not a measure of quality. https://sciencebasedmedicine.org/cbd-oil-the-new-miracle-cure/ https://sciencebasedmedicine.org/cbd-oil-the-new-miracle-cur... What’s the current medical recommendations where you are? I’m not going to guess—too much dodgy advice going around as it is—but best to follow that.
- GekkePrutser 7y agoJust wondering, I use a CPAP machine... If I were to get this, could I use that to keep going at home? (Perhaps with a higher setting). It sounds like the same thing. CPAP masks do leak air but contamination doesn't really matter as I live alone.
- tcbawo 7y agoI don't have medical advice for you (not a doctor), but if you need assistance breathing you should call a doctor immediately. Hopefully, we'll get more guidance as we learn from what is working.
- ta999999171 7y agoWhat an awful response. He's clearly talking about the context in which medical staff are overwhelmed and unavailable.