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>> You're making sure that there are antibodies in there and that they would be effective? > Exactly. Exactly—that we have a potent unit. We think that one pe

• zaroth 7y ago
  Once someone has been exposed and recovered, they should have the antibody concentration required to be become a donor themselves. The required number of cells we’re taking about is high enough that you’re not transfusing A->B and then recovering A from B’s plasma and going on to give A->C. But while B is infected they will make their own antibodies and after they recover they could then be a donor as in B->C. As TFA mentions, China doesn’t even bother testing the level of antibodies, they just collect the plasma from anyone recovered. 90 tons to Italy... is a lot of plasma. At least for IVIG the plasma is pooled from a large number of donors for each transfusion ultimately given to a patient. So it’s more a question of the average antibody load than needing to gauge each individual donor’s levels. > Each IVIG preparation is made from the pooled plasma of 3,000-10,000 blood donors, which is then purified to contain more than 90% antibodies. [1] I think we need to start collecting plasma from recovered positive cases today. I get that for a trial you do want to have a measured baseline of antibodies. But we can start stockpiling and pooling COVID antibody plasma even without the antibody testing. [1] - https://www.rheumaderm-society.org/ivig/ https://www.rheumaderm-society.org/ivig/