13 ms·

Based on unpublished data, and the article neither names the drug nor says anything about the kind of study this claim is based on. Not something to get excite

by hannob 7y ago

Based on unpublished data, and the article neither names the drug nor says anything about the kind of study this claim is based on. Not something to get excited about.

raverbashing 7y ago
I kinda understand wanting to have people not rush to testing the drug, though if both are administered by infusion the risk of self-medication is reduced. Better wait for the article.
- stewbrew 7y ago
  It seems to have been tested in a Chinese hospital before. So there is some experience with these two drugs.
- pjscott 7y ago
  I want people to rush to testing all sorts of drugs, this one included. How quickly should testing of a drug expand? That depends on a balance of risks. The faster you go, the more danger there is of the drug having bad side-effects while you're figuring out how safe and effective it is. The slower you go, the more you delay the possible benefits if the drug ends up working. Right now the potential benefits of such a drug are enormous -- or, put another way, each day of delay is a minor catastrophe. That should tilt the scales a lot. Sometimes the careful, cautious thing to do is to go fast!
  - raverbashing 7y ago
    Clarification, I don't want them to self-test, and I agree with you. I think there's too much hate on that Hydroxycloroquine study and its shortcomings, the risks of testing that are small (though not insignificant and especially not for those with light symptoms) compared to the potential benefits.
mrcode007 7y ago
camostat mesilate
- slowmovintarget 7y ago
  https://en.wikipedia.org/wiki/Camostat https://en.wikipedia.org/wiki/Camostat
- forkexec 7y ago
  Camostat plus E-64d was proposed in a paper in Cell around March 5 as a potential superior prophylaxis under investigation because it blockades the virus from using either ACE2 or TMPRSS2, completely denying SARS-CoV-2 from entering human cells. It's not a vaccine but it seems possible to prevent infection and possibly halt illness. That is, if it doesn't have any yet unknown, horrible side-effects.
- stewbrew 7y ago
  Where did you get this info? According to https://www.tagesspiegel.de/politik/salzburger-mediziner-testen-coronavirus-mittel-praeparat-soll-entzuendungssturm-bremsen-koennen/25656826.html https://www.tagesspiegel.de/politik/salzburger-mediziner-tes... the drugs were Tocilizumab and Remdesivir.
BurningFrog 7y ago
And yet I am excited! Unless I misunderstand the article a lot, this comes from the head of an established hospital, not some Alex Jones equivalent! Sure, it can still turn out to not work. And "90%" may well not be reproducible. But I'd bet a minor sum on this having a real effect.
derkoe 7y ago
They say that they'll publish the results "in the next days". Anyway it seems to work - maybe that's one of the reasons for the low death count (in relation to infected) in Austria so far.

by hannob 7y ago

Based on unpublished data, and the article neither names the drug nor says anything about the kind of study this claim is based on. Not something to get excited about.

raverbashing 7y ago

I kinda understand wanting to have people not rush to testing the drug, though if both are administered by infusion the risk of self-medication is reduced. Better wait for the article.

stewbrew 7y ago
It seems to have been tested in a Chinese hospital before. So there is some experience with these two drugs.
pjscott 7y ago
I want people to rush to testing all sorts of drugs, this one included. How quickly should testing of a drug expand? That depends on a balance of risks. The faster you go, the more danger there is of the drug having bad side-effects while you're figuring out how safe and effective it is. The slower you go, the more you delay the possible benefits if the drug ends up working. Right now the potential benefits of such a drug are enormous -- or, put another way, each day of delay is a minor catastrophe. That should tilt the scales a lot. Sometimes the careful, cautious thing to do is to go fast!
- raverbashing 7y ago
  Clarification, I don't want them to self-test, and I agree with you. I think there's too much hate on that Hydroxycloroquine study and its shortcomings, the risks of testing that are small (though not insignificant and especially not for those with light symptoms) compared to the potential benefits.

mrcode007 7y ago

camostat mesilate

slowmovintarget 7y ago
https://en.wikipedia.org/wiki/Camostat https://en.wikipedia.org/wiki/Camostat
forkexec 7y ago
Camostat plus E-64d was proposed in a paper in Cell around March 5 as a potential superior prophylaxis under investigation because it blockades the virus from using either ACE2 or TMPRSS2, completely denying SARS-CoV-2 from entering human cells. It's not a vaccine but it seems possible to prevent infection and possibly halt illness. That is, if it doesn't have any yet unknown, horrible side-effects.
stewbrew 7y ago
Where did you get this info? According to https://www.tagesspiegel.de/politik/salzburger-mediziner-testen-coronavirus-mittel-praeparat-soll-entzuendungssturm-bremsen-koennen/25656826.html https://www.tagesspiegel.de/politik/salzburger-mediziner-tes... the drugs were Tocilizumab and Remdesivir.

BurningFrog 7y ago

And yet I am excited! Unless I misunderstand the article a lot, this comes from the head of an established hospital, not some Alex Jones equivalent! Sure, it can still turn out to not work. And "90%" may well not be reproducible. But I'd bet a minor sum on this having a real effect.

derkoe 7y ago

They say that they'll publish the results "in the next days". Anyway it seems to work - maybe that's one of the reasons for the low death count (in relation to infected) in Austria so far.