6 ms·

Chloroquine on Google Trends

30 points by hamilyon2 7y ago

zapdrive 7y ago
Does it even work on a Covid-19 infection?
- cjbenedikt 7y ago
  Serious question? People still don't follow relevant news, do they...
  - X6S1x6Okd1st 7y ago
    The evidence that it helps as a treatment is spotty. E.g. https://mobile.twitter.com/GaetanBurgio/status/1241201751916568576 https://mobile.twitter.com/GaetanBurgio/status/1241201751916...
- jimueller 7y ago
  Good question, seems like it's still being determined, but apparently the US president has made some statements that suggest it does. Being a doctor does come naturally to him of course.
- dougmwne 7y ago
  I think the best answer is that it is under study and good science takes time. Initial indications are positive but anecdotal. More data is needed. This is from Dr. Fauci yesterday. There is reasonable hope for better treatments from a range of drugs but for each one you need quality studies to determine the effect size, dosage, risk/benefit, and statistical significance. If we can slow this pandemic we will have more time for the science, plus many other preparations that are happening in hospitals. Wash your hands, limit social contact, stay informed.
- X6S1x6Okd1st 7y ago
  Here's a review of one of the papers that has been causing some of the hype: https://mobile.twitter.com/GaetanBurgio/status/1241201751916568576 https://mobile.twitter.com/GaetanBurgio/status/1241201751916... My layman's understanding is that there is theory to support it and some treatment centers are trying it out, but there isn't quality evidence to suggest wide spread adoption.
psfollow 7y ago
What would explain the differences among the 50 states? There seems to be quite a wide range.
lalaland1125 7y ago
This is actually causing a severe shortage at many pharmacies and hospitals. People are rushing out and hoarding this drug, preventing us from having adequate supplies for treating the serious cases.
- X6S1x6Okd1st 7y ago
  Do you have a citation?
  - roywiggins 7y ago
    https://www.nytimes.com/2020/03/20/health/coronavirus-chloroquine-trump.html https://www.nytimes.com/2020/03/20/health/coronavirus-chloro...
  - casion 7y ago
    https://news.ycombinator.com/item?id=22639267 https://news.ycombinator.com/item?id=22639267
  - quickthrowman 7y ago
    https://www.reddit.com/r/medicine/comments/flor5z/please_stop_prescribing_hydroxychloroquine_for/ https://www.reddit.com/r/medicine/comments/flor5z/please_sto...
- tomerico 7y ago
  Isn't this a prescription controlled drug?
  - lalaland1125 7y ago
    Yes, but many doctors aren't as ethical as they should be.
- IAmEveryone 7y ago
  Even worse, it’s leaving people with Lupus and arthritis in a position to quit the medication that’s keeping them alive/comfortable cold turkey. https://www.nytimes.com/2020/03/20/health/coronavirus-chloroquine-trump.html?action=click&module=Spotlight&pgtype=Homepage https://www.nytimes.com/2020/03/20/health/coronavirus-chloro... And then you get this word salad that sounds like a forward from grandpa, early AOL era (even including all-caps): “HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine. The FDA has moved mountains - Thank You! Hopefully they will BOTH (H works better with A, International Journal of Antimicrobial Agents)” All based on some data from a Petri dish, and a non-randomized trial where they measured “virus load” by eyeballing it: https://mobile.twitter.com/GaetanBurgio/status/1241201751916568576 https://mobile.twitter.com/GaetanBurgio/status/1241201751916... This is insanity, Nero-style (only without actual style). You couldn’t kill more people if you tried.
OnlineCourage 7y ago
It's going to end up killing people. Chloroquine is nasty stuff and irresponsible to be hawking...pharmaceuticals can cause as much damage as they can prevent! There is no clinical basis and Trump continues to hawk it ultimately because he is so vested in hotels and hospitality and is more focused on financial damage control of his own investments than the health and safety of the American people.
- narrator 7y ago
  I really don't get where this comes from. It's a generic drug that's been used for 70 years all over the world in tens of thousands of patients to treat malaria. It's already standard of care in China and South Korea where the recovery rates are high and the death rate is low. I think your extreme Donald Trump hatred is clouding your judgement.
  - OnlineCourage 7y ago
    No, I don't hate anyone. Dosage. I have taken Chloroquine before, it is not as run of the mill as you think. Extreme side effects.
  - JPLeRouzic 7y ago
    I am not a doctor, but there is a book named "Self-determined Dying: Manual for a rational Suicide by Chloroquine". There is also a retinopathy named after Chloroquine: https://en.wikipedia.org/wiki/Chloroquine_retinopathy https://en.wikipedia.org/wiki/Chloroquine_retinopathy
    - narrator 7y ago
      https://www.ncbi.nlm.nih.gov/pubmed/8674334 https://www.ncbi.nlm.nih.gov/pubmed/8674334 You can overdose on it if you take more than 1.7 grams. The recommended dose is 400mg. For reference, you can overdose on tylenol and die if you take 4 times the recommended dosage. The retinopathy happens after several years of taking the drug for rheumatoid arthritis. The course of treatment is six days for coronavirus.
mobilejdral 7y ago
"fever shortness of breath" filtered by metro region has been what I look at every day for more than a month now. It is a window into where community spread has been appearing (and people are googling their symptoms) and it is this weird view into the future of what will be reported in the news. Watching it spread county by county from the main cities to elsewhere in the country has been something. https://trends.google.com/trends/explore?geo=US&q=fever%20shortness%20of%20breath https://trends.google.com/trends/explore?geo=US&q=fever%20sh...
- dougmwne 7y ago
  Yikes Arkansas. That is not good news at all since it is one of the poorest states in the country. Since you've been watching this search trend, do you have any insights you could summarize?
  - mobilejdral 7y ago
    Just because a state has one reported case from one person flying in doesn't mean it was showing up in the community. Florida was showing up early on even before it was being talked about, let alone the weird anti-talking about it they seem to be doing. I would not want to be living there now. Overall it has been playing out like you would imagine. Hot spots with big airports seem to light up first. Then the surrounding areas and slowly spreading out via the highway system. If there every is a real zombie apocalypse West Virginia, Vermont and Wyoming all seem to be the best places to go. I have been taking screenshots since March 11th (when it seemed to suddenly overnight be "everywhere") so you can scroll through and see how quickly this has spread https://imgur.com/gallery/IaFgXiF https://imgur.com/gallery/IaFgXiF
    - dougmwne 7y ago
      This corroborates your observation about Florida: https://healthweather.us/ https://healthweather.us/
chvid 7y ago
HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine. The FDA has moved mountains - Thank You! Hopefully they will BOTH (H works better with A, International Journal of Antimicrobial Agents) be put in use IMMEDIATELY. PEOPLE ARE DYING, MOVE FAST, and GOD BLESS EVERYONE! Wrote president Trump a few hours ago on twitter. I really hope this is right as the two drugs are cheap, generic and have been around for some time.
- m0zg 7y ago
  I propose those who say this doesn't work and "2 grams will kill you" simply tell their doctors to not prescribe the drug, and let the dice fall as they may. You don't have to take it. This will put the current controversy to bed pretty quickly if death rate with is lower than death rate without, which we'll see in as little as 2 weeks. If everyone takes it it'll be much harder to see if it's effective.
- qes 7y ago
  > The FDA has moved mountains... be put in use IMMEDIATELY The FDA didn't really have to do anything. Doctors could prescribe it for off-label use already.
  - chvid 7y ago
    The president really shouldn’t write this stuff in his twitter though: https://www.scmp.com/news/world/africa/article/3076240/coronavirus-nigeria-reports-chloroquine-poisonings-after-donald https://www.scmp.com/news/world/africa/article/3076240/coron... Coronavirus: Nigeria reports chloroquine poisonings after Donald Trump touts antimalarial drug as treatment
    - busymom0 7y ago
      That article is trying so hard. Way too hard. Any drug can kill you if you overdose it. If I remember right, 400 mg is the prescribed dosage. They are trying to make it seem that it can overdose easily but nope - at least 2g is needed to overdose. I can smell their bias in their reporting, they are trying to make the President look bad.
tibbydudeza 7y ago
Trump should leave it to the experts ... he is snake oil huckster.

30 points by hamilyon2 7y ago

zapdrive 7y ago

Does it even work on a Covid-19 infection?

cjbenedikt 7y ago
Serious question? People still don't follow relevant news, do they...
- X6S1x6Okd1st 7y ago
  The evidence that it helps as a treatment is spotty. E.g. https://mobile.twitter.com/GaetanBurgio/status/1241201751916568576 https://mobile.twitter.com/GaetanBurgio/status/1241201751916...
jimueller 7y ago
Good question, seems like it's still being determined, but apparently the US president has made some statements that suggest it does. Being a doctor does come naturally to him of course.
dougmwne 7y ago
I think the best answer is that it is under study and good science takes time. Initial indications are positive but anecdotal. More data is needed. This is from Dr. Fauci yesterday. There is reasonable hope for better treatments from a range of drugs but for each one you need quality studies to determine the effect size, dosage, risk/benefit, and statistical significance. If we can slow this pandemic we will have more time for the science, plus many other preparations that are happening in hospitals. Wash your hands, limit social contact, stay informed.
X6S1x6Okd1st 7y ago
Here's a review of one of the papers that has been causing some of the hype: https://mobile.twitter.com/GaetanBurgio/status/1241201751916568576 https://mobile.twitter.com/GaetanBurgio/status/1241201751916... My layman's understanding is that there is theory to support it and some treatment centers are trying it out, but there isn't quality evidence to suggest wide spread adoption.

psfollow 7y ago

What would explain the differences among the 50 states? There seems to be quite a wide range.

lalaland1125 7y ago

This is actually causing a severe shortage at many pharmacies and hospitals. People are rushing out and hoarding this drug, preventing us from having adequate supplies for treating the serious cases.

X6S1x6Okd1st 7y ago
Do you have a citation?
- roywiggins 7y ago
  https://www.nytimes.com/2020/03/20/health/coronavirus-chloroquine-trump.html https://www.nytimes.com/2020/03/20/health/coronavirus-chloro...
- casion 7y ago
  https://news.ycombinator.com/item?id=22639267 https://news.ycombinator.com/item?id=22639267
- quickthrowman 7y ago
  https://www.reddit.com/r/medicine/comments/flor5z/please_stop_prescribing_hydroxychloroquine_for/ https://www.reddit.com/r/medicine/comments/flor5z/please_sto...
tomerico 7y ago
Isn't this a prescription controlled drug?
- lalaland1125 7y ago
  Yes, but many doctors aren't as ethical as they should be.
IAmEveryone 7y ago
Even worse, it’s leaving people with Lupus and arthritis in a position to quit the medication that’s keeping them alive/comfortable cold turkey. https://www.nytimes.com/2020/03/20/health/coronavirus-chloroquine-trump.html?action=click&module=Spotlight&pgtype=Homepage https://www.nytimes.com/2020/03/20/health/coronavirus-chloro... And then you get this word salad that sounds like a forward from grandpa, early AOL era (even including all-caps): “HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine. The FDA has moved mountains - Thank You! Hopefully they will BOTH (H works better with A, International Journal of Antimicrobial Agents)” All based on some data from a Petri dish, and a non-randomized trial where they measured “virus load” by eyeballing it: https://mobile.twitter.com/GaetanBurgio/status/1241201751916568576 https://mobile.twitter.com/GaetanBurgio/status/1241201751916... This is insanity, Nero-style (only without actual style). You couldn’t kill more people if you tried.

OnlineCourage 7y ago

It's going to end up killing people. Chloroquine is nasty stuff and irresponsible to be hawking...pharmaceuticals can cause as much damage as they can prevent! There is no clinical basis and Trump continues to hawk it ultimately because he is so vested in hotels and hospitality and is more focused on financial damage control of his own investments than the health and safety of the American people.

narrator 7y ago
I really don't get where this comes from. It's a generic drug that's been used for 70 years all over the world in tens of thousands of patients to treat malaria. It's already standard of care in China and South Korea where the recovery rates are high and the death rate is low. I think your extreme Donald Trump hatred is clouding your judgement.
- OnlineCourage 7y ago
  No, I don't hate anyone. Dosage. I have taken Chloroquine before, it is not as run of the mill as you think. Extreme side effects.
- JPLeRouzic 7y ago
  I am not a doctor, but there is a book named "Self-determined Dying: Manual for a rational Suicide by Chloroquine". There is also a retinopathy named after Chloroquine: https://en.wikipedia.org/wiki/Chloroquine_retinopathy https://en.wikipedia.org/wiki/Chloroquine_retinopathy
  - narrator 7y ago
    https://www.ncbi.nlm.nih.gov/pubmed/8674334 https://www.ncbi.nlm.nih.gov/pubmed/8674334 You can overdose on it if you take more than 1.7 grams. The recommended dose is 400mg. For reference, you can overdose on tylenol and die if you take 4 times the recommended dosage. The retinopathy happens after several years of taking the drug for rheumatoid arthritis. The course of treatment is six days for coronavirus.

mobilejdral 7y ago

"fever shortness of breath" filtered by metro region has been what I look at every day for more than a month now. It is a window into where community spread has been appearing (and people are googling their symptoms) and it is this weird view into the future of what will be reported in the news. Watching it spread county by county from the main cities to elsewhere in the country has been something. https://trends.google.com/trends/explore?geo=US&q=fever%20shortness%20of%20breath https://trends.google.com/trends/explore?geo=US&q=fever%20sh...

dougmwne 7y ago
Yikes Arkansas. That is not good news at all since it is one of the poorest states in the country. Since you've been watching this search trend, do you have any insights you could summarize?
- mobilejdral 7y ago
  Just because a state has one reported case from one person flying in doesn't mean it was showing up in the community. Florida was showing up early on even before it was being talked about, let alone the weird anti-talking about it they seem to be doing. I would not want to be living there now. Overall it has been playing out like you would imagine. Hot spots with big airports seem to light up first. Then the surrounding areas and slowly spreading out via the highway system. If there every is a real zombie apocalypse West Virginia, Vermont and Wyoming all seem to be the best places to go. I have been taking screenshots since March 11th (when it seemed to suddenly overnight be "everywhere") so you can scroll through and see how quickly this has spread https://imgur.com/gallery/IaFgXiF https://imgur.com/gallery/IaFgXiF
  - dougmwne 7y ago
    This corroborates your observation about Florida: https://healthweather.us/ https://healthweather.us/

chvid 7y ago

HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine. The FDA has moved mountains - Thank You! Hopefully they will BOTH (H works better with A, International Journal of Antimicrobial Agents) be put in use IMMEDIATELY. PEOPLE ARE DYING, MOVE FAST, and GOD BLESS EVERYONE! Wrote president Trump a few hours ago on twitter. I really hope this is right as the two drugs are cheap, generic and have been around for some time.

m0zg 7y ago
I propose those who say this doesn't work and "2 grams will kill you" simply tell their doctors to not prescribe the drug, and let the dice fall as they may. You don't have to take it. This will put the current controversy to bed pretty quickly if death rate with is lower than death rate without, which we'll see in as little as 2 weeks. If everyone takes it it'll be much harder to see if it's effective.
qes 7y ago
> The FDA has moved mountains... be put in use IMMEDIATELY The FDA didn't really have to do anything. Doctors could prescribe it for off-label use already.
- chvid 7y ago
  The president really shouldn’t write this stuff in his twitter though: https://www.scmp.com/news/world/africa/article/3076240/coronavirus-nigeria-reports-chloroquine-poisonings-after-donald https://www.scmp.com/news/world/africa/article/3076240/coron... Coronavirus: Nigeria reports chloroquine poisonings after Donald Trump touts antimalarial drug as treatment
  - busymom0 7y ago
    That article is trying so hard. Way too hard. Any drug can kill you if you overdose it. If I remember right, 400 mg is the prescribed dosage. They are trying to make it seem that it can overdose easily but nope - at least 2g is needed to overdose. I can smell their bias in their reporting, they are trying to make the President look bad.

tibbydudeza 7y ago

Trump should leave it to the experts ... he is snake oil huckster.