I agree. For example Hipmunk's (http://himpunk.com http://himpunk.com) UI doesn't follow a conventional fixed grid, because it wouldn't make sense. As for defr

I agree. For example Hipmunk's (http://himpunk.com http://himpunk.com) UI doesn't follow a conventional fixed grid, because it wouldn't make sense. As for defroost, I don't think that's what he meant, but I'll let him speak for himself.