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He would have lost his sons college thition then. Mitochondrial _inhibition_ is actually more correlated with longevity than the other way around. If more mito
by ramraj07 7y ago
He would have lost his sons college thition then. Mitochondrial _inhibition_ is actually more correlated with longevity than the other way around.
If more mitochondria meant more efficient working muscle tissue, then that's what we would have evolved, there's always a compromise. Are you sure you can keep the same power output for a given mass and volume of muscle if you keep increasing mitochondrial numbers? Even the reddit answer clearly says that the heart muscle is rate limited by oxygenation (they have more mitochondria but are also highly vascularized to power the mitochondria). More mitochondria===more power doesn't mean it's better for us, physiology is rarely that simple.
- catalogia 7y ago> Mitochondrial _inhibition_ is actually more correlated with longevity than the other way around. Longevity is overrated. The light that burns twice as bright lives half as long. I'd rather be a superhuman for 40 years than feeble for 120 years.
- TheSpiceIsLife 7y agoAs I understand it, longevity in the life-extension sense is generally taken to mean years of good health. Edit: fixed a word.
- goatinaboat 7y agoI'd rather be a superhuman for 40 years than feeble for 120 years. But that’s not a choice you can actually make, it’s out of your control. What if you could choose by taking a pill?
- rubber_duck 7y agoSteroids let you control this trade-off
- ci5er 7y agoMaybe yes, maybe no. But evolution didn't decide on the structure and behavior of our throw-away-cup bodies in order to make our puny minds sitting on top our puny brains happy. For better or for worse, in humans (we are not turtles, for example, they have their own success strategy), AVERAGE 2nd generation reproductive success is the measure of our existence. The collection of strategies to maximize that are different for human men and human women. But aligned. On average. 2nd-generation reproductive success is our "purpose" in a universe made mostly out of hydrogen. Nothing more - nothing less.
- NotSammyHagar 7y agoI'd rather be healthy for 120 years like I am now, yet could live with never being a superhuman.
- TheSpiceIsLife 7y ago> if you want to have a superhuman composition You responded to a bunch of claims the comment didn’t make.
- at5kj5rtjarjhw4 7y agoSpecifically it is due to reproductive defects in mitochondrial dna as one ages. Anti-aging researcher Aubrey de Gray has a talk on this specific issue: https://www.youtube.com/watch?v=Pm_LboN6eZM https://www.youtube.com/watch?v=Pm_LboN6eZM
- adrianN 7y agoHuman evolution happened almost exclusively during times where food was scarce.