4 ms·

Since this 13th of February, the Koreans recommend the use of hydrochloroquine for patients infected by the covid-19 [1]. The Covid-19 fatality ratio in Korea i

Since this 13th of February, the Koreans recommend the use of hydrochloroquine for patients infected by the covid-19 [1]. The Covid-19 fatality ratio in Korea is one of the lowest in the world, around 1%. The study in France showing a spectacular drop in covid-19 viral load after only 6 days of hydrochloroquine treatment has been directed by Pr Didier Raoult who is the most cited researcher on infectious disease in the world. [2] Anecdotally, I personally know a patient who took hydrochloroquine, and indeed the viral load dropped quickly, even though the lung damage is still there. According to Pr Didier Raoult, the hydrochloroquine has been routinely prescribed for decades to prevent Malaria, with well known and limited side-effects. According to him, the in-vitro effectiveness of hydrochloroquine on covid-19 has been confirmed by several labs independently, including his own lab and the lab of Mr Zong the most cited researcher on infectious disease in China. (Sorry, I am not sure about the spelling) [1] http://m.koreabiomed.com/news/articleView.html?idxno=7428 http://m.koreabiomed.com/news/articleView.html?idxno=7428 [2] https://scholar.google.fr/citations?user=n8EF_6kAAAAJ&hl=fr https://scholar.google.fr/citations?user=n8EF_6kAAAAJ&hl=fr

deleted 7y ago
[deleted]
roenxi 7y ago
I'm reminded of the old armour-where-the-bullets-aren't story [0]. The most important things to watch out for are places where symptoms don't show up at all. One interesting challenge that the people doing studies must be facing is that by the time symptoms get bad the virus is probably to some degree irrelevant. If someone's lungs have given out then whether or not there are virus particles in their body probably doesn't matter so much; the damage is done. Raw viral load isn't putting people in hospital as much as that important parts of their body have been dissolved. For a drug to be effective against the virus maybe it needs to be cheap & administered very early before symptoms become too obvious. That'd be hard to study. [0] https://medium.com/@penguinpress/an-excerpt-from-how-not-to-be-wrong-by-jordan-ellenberg-664e708cfc3d https://medium.com/@penguinpress/an-excerpt-from-how-not-to-...
- kayamon 7y ago
  There's actually a team at the University of Minnesota doing that study right now. https://www.reddit.com/r/medicine/comments/fkb0wa/university_of_minnesota_covid10/ https://www.reddit.com/r/medicine/comments/fkb0wa/university...
sansnom 7y ago
So true. I hope we could listen to real expert (like Pr Didier Raoult) instead of so called expert like this Derek Lowe (PhD in organic chemistry, he is no expert in infectious disease at all). In France, when Pr Didier Raoult in 25th of February [0] said that the chinese found that chloroquine was effective like it is effective against SARS-CoV (2003) [1], it was considered a fake news by "Le Monde" one of the most read journal in France... Only now, because he has published a study [2], people are starting to say: "may be we need to check further"... Everybody was saying: "Yeah, but there is side effect". Their team has used this drug for decade and know exactly how it works and how to use it... So people, please, please, let's the real expert do the talking. [0] https://www.mediterranee-infection.com/coronavirus-vers-une-sortie-de-crise/ https://www.mediterranee-infection.com/coronavirus-vers-une-... [1] https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69 https://virologyj.biomedcentral.com/articles/10.1186/1743-42... [2] https://www.mediterranee-infection.com/hydroxychloroquine-and-azithromycin-as-a-treatment-of-covid-19/ https://www.mediterranee-infection.com/hydroxychloroquine-an...
banannaise 7y ago
Presently, I would think fatality rates mostly measure testing penetration, not treatment effectiveness. A country that's testing everyone will show a much lower fatality rate than a country testing only the sickest people, because the latter countries have few to no confirmed minor cases.

deleted 7y ago

[deleted]

roenxi 7y ago

I'm reminded of the old armour-where-the-bullets-aren't story [0]. The most important things to watch out for are places where symptoms don't show up at all. One interesting challenge that the people doing studies must be facing is that by the time symptoms get bad the virus is probably to some degree irrelevant. If someone's lungs have given out then whether or not there are virus particles in their body probably doesn't matter so much; the damage is done. Raw viral load isn't putting people in hospital as much as that important parts of their body have been dissolved. For a drug to be effective against the virus maybe it needs to be cheap & administered very early before symptoms become too obvious. That'd be hard to study. [0] https://medium.com/@penguinpress/an-excerpt-from-how-not-to-be-wrong-by-jordan-ellenberg-664e708cfc3d https://medium.com/@penguinpress/an-excerpt-from-how-not-to-...

kayamon 7y ago
There's actually a team at the University of Minnesota doing that study right now. https://www.reddit.com/r/medicine/comments/fkb0wa/university_of_minnesota_covid10/ https://www.reddit.com/r/medicine/comments/fkb0wa/university...

sansnom 7y ago

So true. I hope we could listen to real expert (like Pr Didier Raoult) instead of so called expert like this Derek Lowe (PhD in organic chemistry, he is no expert in infectious disease at all). In France, when Pr Didier Raoult in 25th of February [0] said that the chinese found that chloroquine was effective like it is effective against SARS-CoV (2003) [1], it was considered a fake news by "Le Monde" one of the most read journal in France... Only now, because he has published a study [2], people are starting to say: "may be we need to check further"... Everybody was saying: "Yeah, but there is side effect". Their team has used this drug for decade and know exactly how it works and how to use it... So people, please, please, let's the real expert do the talking. [0] https://www.mediterranee-infection.com/coronavirus-vers-une-sortie-de-crise/ https://www.mediterranee-infection.com/coronavirus-vers-une-... [1] https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69 https://virologyj.biomedcentral.com/articles/10.1186/1743-42... [2] https://www.mediterranee-infection.com/hydroxychloroquine-and-azithromycin-as-a-treatment-of-covid-19/ https://www.mediterranee-infection.com/hydroxychloroquine-an...

banannaise 7y ago

Presently, I would think fatality rates mostly measure testing penetration, not treatment effectiveness. A country that's testing everyone will show a much lower fatality rate than a country testing only the sickest people, because the latter countries have few to no confirmed minor cases.