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Or none of the above. So, you can apply statistics to medicine in the form of incidence of a disease, and likelihood ratios to increase or decrease the chance o
by Engineering-MD 7y ago
Or none of the above. So, you can apply statistics to medicine in the form of incidence of a disease, and likelihood ratios to increase or decrease the chance of disease in diagnosis.
The problem is, the data for these is so difficult to interpret. Likelihood ratios in papers often have huge confidence intervals (like anywhere from 2-15), making their use problematic. Then often, they are quoted only for very specific patient groups, and applying them out of these groups invalidates the rule.
Then things like prognosis are so variable, taking quantitively becomes a bit pointless. It’s especially true in cases where treatment or investigations are changing constantly, such as cancer.
For diagnosis, the history is often more useful. Humans are story tellers, and the description of the problem varies hugely between patients, as does the significance of certain symptoms or descriptions. It’s an art to work out what is the real symptom and what isn’t. To work out the real picture isn’t always easy either.
Ultimately for things where there is relatively good evidence to practice statistics they are made into algorithms (see MDCalc for examples) but again it’s hard to apply them out of the correct patient population. Even these rules seem to poorly apply in many situations.
Then, real hard statistics rarely change management. You think of the reasonable causes and risk reduce as far as possible. Knowing the actual probability doesn’t really change what you can do. Same kind of goes for prognosis. Most patients don’t really know what to do with exact numbers (especially when they vary so much between different patients).
So, ultimately this is why doctors don’t use statistics regularly.
- beefield 7y agoSorry, but that is to me a textbook example of what I think as case 2. It is not about hard statistics. It is your job to translate all those uncertainties and sources of knowledge to (subjective) probabilities. If you do not do that, you are doing things wrong. I do not see how there is anything to even discuss here. Probabilities are the current best tool we have to work with uncertainties. I do not hire a doctor to just tell me what will be done. I hire a doctor as a consultant to give advice what he thinks is wise given his knowledge and then I do the decision what I do with my body and life. And the consultant should damn well give the best available information he has, just not think that I am so dumb that I can't decide myself.[1] (Again, sorry for the rant, I have been way too frustrated on this specific issue earlier in my life) [1] Obviously, most of the time I do agree with doctor's recommendations. But if I am one day having a cancer and a doctor refuses to estimate the odds for me living another month, year and decade, strong verbal abuse is given.