Screen readers and accessibility software have never worked well* with arbitrary applications, and that’s what sites using the shadow dom aim to be. Screen rea

Screen readers and accessibility software have never worked well* with arbitrary applications, and that’s what sites using the shadow dom aim to be. Screen readers especially only do well on simple documents, and only work with apps well they’re specifically designed to interface with which for the most part are apps that are used in document creation or text communication like Word, or Skype. *Disclaimer: “well” is in the eye of the beholder. It’s challenging to use them with arbitrary apps, and the time investment is only useful if that app is going to put food into your table.