3 ms·
> The current tests have a 0% false positive rate. Need a citation on this. In order to even make a strong statement about the false positive rate you need to
by andrewla 7y ago
> The current tests have a 0% false positive rate.
Need a citation on this. In order to even make a strong statement about the false positive rate you need to have some sort of alternate confirmation mechanism, usually clinical diagnosis or another more comprehensive test. That kind of work takes time and we haven't gotten to the point where we know this.
False positives in the test are one possible reason for the resurgence in Singapore; the initial screenings were overreporting the number of cases leading to a false sense of security, followed by a surge in real cases as the spread continued.
EDIT: A quick look at some of the tests available indicate that currently providers are not publishing specificity/sensitivity numbers in general under the accelerated release guidelines. One I did find was biomedomics test [1], which claims "The overall testing sensitivity was 88.66% and specificity was 90.63%", so ~10% of negative cases will show as positive.
[1] https://www.biomedomics.com/products/infectious-disease/covid-19-rt/ https://www.biomedomics.com/products/infectious-disease/covi...
- makomk 7y agoThat's an antibody-based test not approved for diagnostic use in the US, which is faster but less accurate than the RT-PCR ones currently being used.
- andrewla 7y agoIt's just the only one that I could get numbers on. So... show me sensitivity/specificity numbers that show a 0% false positive rate. The CDC PCR test [1], for example, has some data and no false positives, but the sample sizes are so small (107 known negatives tested) that the best we can estimate is ~96% specificity. [1] https://www.fda.gov/media/134922/download https://www.fda.gov/media/134922/download