3 ms·
A virologist gives a different view in this thread: https://twitter.com/angie_rasmussen/status/1238946940882006016 https://twitter.com/angie_rasmussen/status/1
by FeteCommuniste 7y ago
A virologist gives a different view in this thread:
https://twitter.com/angie_rasmussen/status/1238946940882006016 https://twitter.com/angie_rasmussen/status/12389469408820060...
Btw, ACE2 expression is decreased in unmedicated diabetics and HTN patients and the elderly which would imply that those groups should have some degree of protection from the virus (ceteris paribus, obviously). In fact that seems to be exactly the opposite of what we see. Some research even indicates that ACE2 could help prevent ARDS-induced lung injury:
https://www.nature.com/articles/srep27911 https://www.nature.com/articles/srep27911
But in that article the injury wasn't induced by COVID-19 so really we don't know enough yet.
(Ref. for decreased ACE2 expression in diabetes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992757/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992757/)