3 ms·
Very cool article summarizing potential of remdesivir as potential therapeutic vs Covid19. Submitted 16-Feb-2020, published 6-Mar-2020, and as of today 15-Mar-2
by 100ideas 7y ago
Very cool article summarizing potential of remdesivir as potential therapeutic vs Covid19. Submitted 16-Feb-2020, published 6-Mar-2020, and as of today 15-Mar-2020, it is the third-most-recently published article about remdesivir vs covid19 as indexed by google scholar [1].
interesting notes: remdesivir was given to the first reported covid19 patient in the usa under a compassionate use exception. Impossible to say if it helped, but the patient's condition did improve the next day.
> "Treatment with intravenous remdesivir (a novel nucleotide analogue prodrug in development) was initiated on the evening of day 7 (illness day 11), and no adverse events were observed in association with the infusion." [2]
Also see "Therapeutic options for the 2019 novel coronavirus (2019-nCoV)" [3]
[1] https://scholar.google.com/scholar?hl=en&as_sdt=0,5&q=remdesivir+&scisbd=1 https://scholar.google.com/scholar?hl=en&as_sdt=0,5&q=remdes...
[2] https://www.nejm.org/doi/10.1056/NEJMoa2001191 https://www.nejm.org/doi/10.1056/NEJMoa2001191
[3] https://www.nature.com/articles/d41573-020-00016-0 https://www.nature.com/articles/d41573-020-00016-0
- 100ideas 7y agothe following article, published 13 Feb 2020, provides an exhaustive list of potential covid19 therapeutics, including remdesivir and a variety of other antivirals. Zhang, L, Liu, Y. Potential interventions for novel coronavirus in China: A systematic review. J Med Virol. 2020; 1– 12. https://doi.org/10.1002/jmv.25707 https://doi.org/10.1002/jmv.25707 open access via publisher: https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.25707 https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.25707)