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If you are interested in the details of how SARS-CoV-2 works, the history of discovery of the ACE2 receptor it binds to, and a potential treatment based on huma
by dharma1 7y ago
If you are interested in the details of how SARS-CoV-2 works, the history of discovery of the ACE2 receptor it binds to, and a potential treatment based on human recombinant ACE2 that has been through phase I and II human trials previously and is now starting trials in China for covid19 - I highly recommend this video lecture from Dr Josef Penninger from earlier this week.
You might need to register (it's free) to watch but it's worth it.
https://connect.myesr.org/course/novel-coronavirus-outbreak-experience-and-challenges-in-imaging-and-beyond/ https://connect.myesr.org/course/novel-coronavirus-outbreak-...
The idea is that by adding soluble rhACE2 to the serum, the virus will bind to that rather than real ACE2 in the cells, reducing viral load.
This is not the flu - it can attack multiple organs where ACE2 is expressed - deep in the lungs, heart, stomach lining, kidneys. I've seen other studies which indicated it can affect the central nervous system too. It's not as deadly as SARS but much more contagious. And we still don't have a clear picture what permanent lung/organ damage is inflicted to some recovered patients.
- dharma1 7y agoNow on YouTube: https://youtu.be/jAW6VBWTiAA https://youtu.be/jAW6VBWTiAA