3 ms·
A really exiting small molecule drug has just been described, which, if this holds up in human trials, could treat the root cause of Huntington’s disease. Rathe
by car 7y ago
A really exiting small molecule drug has just been described, which, if this holds up in human trials, could treat the root cause of Huntington’s disease. Rather unexpected how this works, even in postmitotic tissue, like the brain.
https://www.sickkids.ca/aboutsickkids/newsroom/past-news/2020/huntingtons-dna-repeat-mutations.html https://www.sickkids.ca/aboutsickkids/newsroom/past-news/202...
https://resou.osaka-u.ac.jp/en/research/2020/20200215_1 https://resou.osaka-u.ac.jp/en/research/2020/20200215_1
Review: https://www.nature.com/articles/s41588-020-0577-6 https://www.nature.com/articles/s41588-020-0577-6
Publication: https://doi.org/10.1038/s41588-019-0575-8 https://doi.org/10.1038/s41588-019-0575-8
(To read paywalled papers, sci-hub.tw is your friend, if substituted for doi.org)