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> Metformin is a pretty serious drug and that is a high dose. According to a former endocrinologist of mine, 1000mg daily is the lowest effective dose. 500mg

> Metformin is a pretty serious drug and that is a high dose. According to a former endocrinologist of mine, 1000mg daily is the lowest effective dose. 500mg pills are the lowest dose available. What is your source for 1000mg being a "high dose"?

Spooky23 7y ago
For diabetes or PCOS, sure. What is the effective dose for general life extension?