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I think sampo gave a concise explanation- I tried to clarify the terminology and mechanics around gain of function-loss of function in my comment below (since I
by vikramkr 7y ago
I think sampo gave a concise explanation- I tried to clarify the terminology and mechanics around gain of function-loss of function in my comment below (since I think function means different thing to different people) - basically, there's potentially a mutation in those spike proteins that makes the virus more infective if it turns out to be supported by lab experiements, gain of function just means that the mutation makes the protein work better or gives it a new functionality instead of breaking it.