12 ms·
Haunted by a Gene
- car 7y agoA really exiting small molecule drug has just been described, which, if this holds up in human trials, could treat the root cause of Huntington’s disease. Rather unexpected how this works, even in postmitotic tissue, like the brain. https://www.sickkids.ca/aboutsickkids/newsroom/past-news/2020/huntingtons-dna-repeat-mutations.html https://www.sickkids.ca/aboutsickkids/newsroom/past-news/202... https://resou.osaka-u.ac.jp/en/research/2020/20200215_1 https://resou.osaka-u.ac.jp/en/research/2020/20200215_1 Review: https://www.nature.com/articles/s41588-020-0577-6 https://www.nature.com/articles/s41588-020-0577-6 Publication: https://doi.org/10.1038/s41588-019-0575-8 https://doi.org/10.1038/s41588-019-0575-8 (To read paywalled papers, sci-hub.tw is your friend, if substituted for doi.org)
- tectonic 7y ago> “Enjoy life while you can,” she advises. “Find what gives you some pleasure and go for it."