4 ms·
I'm incredibly ignorant, can someone explain why a drug used to treat arthritis might work against a Coronavirus? I just don't understand the connection/interac
by Someone1234 7y ago
I'm incredibly ignorant, can someone explain why a drug used to treat arthritis might work against a Coronavirus? I just don't understand the connection/interaction, or why this was even tried originally?
Genuinely looking to learn.
- tbarbugli 7y agoit reduces the immune system reaction inflammatory reaction which can be fatal
- J_cst 7y agoThe linked video has interesting explanation. Perhaps someone more versed may upload to YT to get a robotraslation to everybody's benefit?
- DrNuke 7y agoThe two doctors in the video say that it interferes with a similar auto-immune reaction that happens at pulmonary level because of the Coronavirus, so that it works.
- autojoechen 7y agoOne of the ways the virus kills the patient is causing a cytokine storm [0][1]. And tocilizumab suppresses one of the cytokines in humans [2]. 0: https://www.nationalgeographic.com/science/2020/02/here-is-what-coronavirus-does-to-the-body/ https://www.nationalgeographic.com/science/2020/02/here-is-w... 1: https://en.wikipedia.org/wiki/Cytokine_release_syndrome https://en.wikipedia.org/wiki/Cytokine_release_syndrome 2: https://en.wikipedia.org/wiki/Tocilizumab https://en.wikipedia.org/wiki/Tocilizumab
- listsfrin 7y ago"It might be a cytokine storm".
- BjoernKW 7y agoRheumatoid arthritis is an autoimmune disorder. The severe cases who contracted the Coronavirus seem to experience an autoimmune reaction towards otherwise healthy lung tissue.
- inferiorhuman 7y agocan someone explain why a drug used to treat arthritis Rheumatoid arthritis is an autoimmune disease and not a "oh I'm old and I've worn down all of my cartilage" disease.