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I don't think that your example of Sickle Cell (SCD) is a good comparison to the original quote: > how an ethnicity affects the virus spread and severity … cer
by rovolo 7y ago
I don't think that your example of Sickle Cell (SCD) is a good comparison to the original quote:
> how an ethnicity affects the virus spread and severity … certain communities are more endangered than others.
SCD is a genetic disease. It is prevalent in specific regions where malaria is common because SCD protects against malaria. There aren't a suite of genes which make people more susceptible to SCD, there's a single inherited gene which causes SCD. You can't catch SCD from another person unless you inherited their genes.
COVID-19 is a flu virus transmitted from person to person. There's no single gene which makes people more likely to catch or transmit flu. There may be multiple genes which increase susceptibility, but once you start talking about a suite of genetics, ethnicity essentially stops being a factor. (Unless those genes directly influence a survival trait for the local area, such as skin color.) There is too much genetic variation within ethnic groups compared to global variation to single out any groups due to genetics.
- blowski 7y agoThanks for the extra detail. The reason I'd even heard of it is because my wife was tested for it while pregnant, because she has some African ancestry. It's the only case I know of where that kind of racial origin affected susceptibility to any kind of condition. Do you know if there are any known patterns for certain groups having different levels of protection against respiratory viruses? I'm trying to phrase this carefully, as I'm genuinely interested, and don't want to come off as some Infowars-style nutjob.