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It’s the latter. The coronavirus is also responsible for SARS and MERS. They had good luck with a vaccine for SARS but it wasn’t needed anymore so they stopped
by selectodude 7y ago
It’s the latter.
The coronavirus is also responsible for SARS and MERS. They had good luck with a vaccine for SARS but it wasn’t needed anymore so they stopped. MERS is highly lethal and was something they wanted a vaccine for if it popped back up. Ideally (this is where my knowledge stops) the vaccines they were working on for other strains will be a good launching pad to make a vaccine for COVID-19.
- allovernow 7y agoAFAIK the closest they got to working vaccines for SARS and MERS cause lung damage from autoimmune response in each tested animal model. The issue with these viruses is that they have a property known as Antibody Dependent Enhancement (ADE). Where normally neutralizing antibodies instead facilitate entry into your cells.
- selectodude 7y agoThat was a big issue early on, but I think they were able to work past it before funding and interest dried up.
- vorticalbox 7y agoDidn't the SARS vaccine also cause the host to die when reinfected?
- selectodude 7y agoEarly versions were causing even more extreme cytokine storms than the SARS virus did without the vaccine. This shit is trial and error with some difficult to handle results when things are still in development. Which is why the idea that we'll have a safe and effective vaccine within the year is a complete pipe dream.
- econcon 7y agoMERS outbreak keeps happening again and again.