Exactly! This high level model doesn’t draw on any quantum specific phenomena and is in many ways comparable to other stochastic dynamical models that have been

Exactly! This high level model doesn’t draw on any quantum specific phenomena and is in many ways comparable to other stochastic dynamical models that have been developed to explain the non-Arrhenius behavior of protein folding using classical Langevin theory. To argue for the inclusion of quantum theory in explaining protein dynamics is to assert that proteins undergo classically forbidden conformational transitions. The authors of the paper have provided no evidence for such transitions nor even hypothesized about how such transitions could arise. Their only argument against a classical description of protein folding is the inability of molecular dynamics simulations to model the folding-kinetics of some proteins. Seeing as molecular dynamics force fields only provide a rough and approximate description of the forces between atoms within a protein it should be no surprise these methods can’t accurately model the intricate conformational transitions in protein folding.