4 ms·

It is interesting to me that people are so laser focused on test kits and vaccines. In my less than humble opinion, people should focus on improving their immu

It is interesting to me that people are so laser focused on test kits and vaccines. In my less than humble opinion, people should focus on improving their immune system. You can reduce the load on your immune system by not eating sugar and reducing carbs as much as you can. We also know from history and science that every plague that killed people from respiratory virus infections was due to a lack of vitamin D3 and over production of the ACE2 enzyme. The virus quickly binds to ACE2 and their adaptive immune systems did not have the time to start producing enough anti-bodies. I do not understand why the CDC is not suggesting that folks increase their D3 intake, cut out sugar and most importantly, take a break from smoking which is know to increase ACE2. There are alternate methods of nicotine sources available. I mention this because a vaccine is only useful for known viral code. nCoV will have a family of hundreds of variants in no time. Boosting ones built in adaptive defenses will protect against all of the mutations.

LinuxBender 7y ago
Not sure why this is so taboo, I know there are molecular biologists on this site. Anyway, Zinc is the only thing that will slow the RNA transcoding process of the virus in your lungs, but getting enough zinc into cells is hard. You can use a prescription drug Chloroquine to improve the transport, but it has nasty side effects. Vitamin D3 isn't a vitamin at all. It is a precursor to the hormone 25 hydroxy. That is used by several hundred functions in your body, including your adaptive immune system, in conjunction with L-Glutamine to produce white blood cells and much more than I could cover on HN. The virus binds quite easily to ACE2, so you have to slow that down enough that your adaptive immune system can keep up. Smokers and obese people and eldery have the most ACE2 from lung inflammation. Some things to watch or look at CoV Map: https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6 https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.h... CoV Rates: https://www.worldometers.info/coronavirus/ https://www.worldometers.info/coronavirus/ Mutations: https://nextstrain.org/ncov https://nextstrain.org/ncov MedCram: https://www.youtube.com/user/MEDCRAMvideos/videos https://www.youtube.com/user/MEDCRAMvideos/videos The mutations are probably the most interesting. I would be curious what company is going to cover all of them in a vaccine.
malkia 7y ago
as someone on low-carb I find this interresting, but any studies behind it?
- wbg34 7y ago
  This was making the rounds a few days ago in my low carb FB group. I haven't looked into it too much, but it sounded intriguing. https://www.sciencedaily.com/releases/2019/11/191115190327.htm https://www.sciencedaily.com/releases/2019/11/191115190327.h...
- _jal 7y ago
  I'm sure if you check your spam folder or follow links from Twitter bots, you'll find some soon enough.
hprotagonist 7y ago
Cite every sentence above, please, or cut out the idle speculation; it's foolish at best. NPIs -- handwashing, avoiding close contact with people sneezing like mad, not touching your face -- are the only things that actually work right now that everyone can and should be doing.
- francisofascii 7y ago
  It has been widely reported that CORVID-19 affects the lungs, and that smoking may play a role in the severity of symptoms. Also there have been plenty of studies linking high sugar diets with reduced immune response.
AdmiralGinge 7y ago
>most importantly, take a break from smoking which is know to increase ACE2 Not going to lie, I'm very very glad I quit smoking before this coronavirus business. I was down to just a vape by June last year and I quit that in December.
herf 7y ago
Here are three negative results (all randomized controlled trials) for Vitamin D supplementation during the winter: https://www.frontiersin.org/articles/10.3389/fimmu.2019.00065/full https://www.frontiersin.org/articles/10.3389/fimmu.2019.0006... failed to show any effect on wintertime supplementation of D (using pre-registered criteria) http://www.vitaminedelft.org/files/art/ling2009.pdf http://www.vitaminedelft.org/files/art/ling2009.pdf "no benefit" https://pubs.rsc.org/en/content/articlelanding/2014/fo/c4fo00371c/unauth#!divAbstract https://pubs.rsc.org/en/content/articlelanding/2014/fo/c4fo0... "did not lower incidence of influenza"
- LinuxBender 7y ago
  It would be no benefit to anyone that is not already deficient. [1] [1] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075634/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075634/
- belltaco 7y ago
  Here's a positive result. https://www.bmj.com/content/356/bmj.i6583 https://www.bmj.com/content/356/bmj.i6583 "Vitamin D supplementation was safe and it protected against acute respiratory tract infection overall. Patients who were very vitamin D deficient and those not receiving bolus doses experienced the most benefit."
  - herf 7y ago
    Good one (odds ratio=0.88), and it's generally low-risk.
BlargMcLarg 7y ago
I'm curious how this is the conclusion you made instead of becoming more macro-organized. People are getting more and more stressed (see burn-outs rising), affecting our immune systems. Most of us are still encouraged to go into work when we have a cold. Many could work from home, but are actively or passively stigmatized when attempting to do so. For all its draconian measures, China is showing them to be effective for the time being. In the same way, we could've rid ourselves of many pests, plagues and illnesses ages ago which a simple "get your immune system up bro" couldn't deal with.
bilekas 7y ago
> people should focus on improving their immune system Okay, but for those who cant, underlining conditions etc, what do you suggest ? This is the world we live in, and that kind of build up you're talking about that would fight off all these strains of virus' would take generations of active measures. In the meantime, I don't think it's a bad idea to develop vaccines and shots which will aid our immune system. Our body uses the memory DNA (or memory cells - Not a doctor) after getting chicken-pox so that we (usually) don't get it again. But the COVID strains vary so much it's a little pie-in-the sky right now to imagine naturally fighting all of them. Our best defense is our ability to maintain good hygiene in this generation. We know all about how these things spread, and that should be the primary focus for the every day to day person.
- LinuxBender 7y ago
  Everyone will eventually get one of the mutations. [1] Maybe a vaccine will cover all of them some day. In the mean time, everyone, especially those with pre-exisiting conditions should be focusing on removing burdens from their immune system (sugar, carbs, anything that spikes insulin), getting a LOT of sleep, and ensuring they are not deficient in D3, Zinc, L-Glutamine, Magnesium, well, all the essential minerals, vitamins and enzymes. I have not had a vaccine since the 1990's and I have only noticeably had the flu twice (h1n1, h3n2) and even then it just made me gassy. I went home as a courtesy to my coworkers. I have not had a cold in 15 years. [1] - https://nextstrain.org/ncov https://nextstrain.org/ncov

LinuxBender 7y ago

Not sure why this is so taboo, I know there are molecular biologists on this site. Anyway, Zinc is the only thing that will slow the RNA transcoding process of the virus in your lungs, but getting enough zinc into cells is hard. You can use a prescription drug Chloroquine to improve the transport, but it has nasty side effects. Vitamin D3 isn't a vitamin at all. It is a precursor to the hormone 25 hydroxy. That is used by several hundred functions in your body, including your adaptive immune system, in conjunction with L-Glutamine to produce white blood cells and much more than I could cover on HN. The virus binds quite easily to ACE2, so you have to slow that down enough that your adaptive immune system can keep up. Smokers and obese people and eldery have the most ACE2 from lung inflammation. Some things to watch or look at CoV Map: https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6 https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.h... CoV Rates: https://www.worldometers.info/coronavirus/ https://www.worldometers.info/coronavirus/ Mutations: https://nextstrain.org/ncov https://nextstrain.org/ncov MedCram: https://www.youtube.com/user/MEDCRAMvideos/videos https://www.youtube.com/user/MEDCRAMvideos/videos The mutations are probably the most interesting. I would be curious what company is going to cover all of them in a vaccine.

malkia 7y ago

as someone on low-carb I find this interresting, but any studies behind it?

wbg34 7y ago
This was making the rounds a few days ago in my low carb FB group. I haven't looked into it too much, but it sounded intriguing. https://www.sciencedaily.com/releases/2019/11/191115190327.htm https://www.sciencedaily.com/releases/2019/11/191115190327.h...
_jal 7y ago
I'm sure if you check your spam folder or follow links from Twitter bots, you'll find some soon enough.

hprotagonist 7y ago

Cite every sentence above, please, or cut out the idle speculation; it's foolish at best. NPIs -- handwashing, avoiding close contact with people sneezing like mad, not touching your face -- are the only things that actually work right now that everyone can and should be doing.

francisofascii 7y ago
It has been widely reported that CORVID-19 affects the lungs, and that smoking may play a role in the severity of symptoms. Also there have been plenty of studies linking high sugar diets with reduced immune response.

AdmiralGinge 7y ago

>most importantly, take a break from smoking which is know to increase ACE2 Not going to lie, I'm very very glad I quit smoking before this coronavirus business. I was down to just a vape by June last year and I quit that in December.

herf 7y ago

Here are three negative results (all randomized controlled trials) for Vitamin D supplementation during the winter: https://www.frontiersin.org/articles/10.3389/fimmu.2019.00065/full https://www.frontiersin.org/articles/10.3389/fimmu.2019.0006... failed to show any effect on wintertime supplementation of D (using pre-registered criteria) http://www.vitaminedelft.org/files/art/ling2009.pdf http://www.vitaminedelft.org/files/art/ling2009.pdf "no benefit" https://pubs.rsc.org/en/content/articlelanding/2014/fo/c4fo00371c/unauth#!divAbstract https://pubs.rsc.org/en/content/articlelanding/2014/fo/c4fo0... "did not lower incidence of influenza"

LinuxBender 7y ago
It would be no benefit to anyone that is not already deficient. [1] [1] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075634/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075634/
belltaco 7y ago
Here's a positive result. https://www.bmj.com/content/356/bmj.i6583 https://www.bmj.com/content/356/bmj.i6583 "Vitamin D supplementation was safe and it protected against acute respiratory tract infection overall. Patients who were very vitamin D deficient and those not receiving bolus doses experienced the most benefit."
- herf 7y ago
  Good one (odds ratio=0.88), and it's generally low-risk.

BlargMcLarg 7y ago

I'm curious how this is the conclusion you made instead of becoming more macro-organized. People are getting more and more stressed (see burn-outs rising), affecting our immune systems. Most of us are still encouraged to go into work when we have a cold. Many could work from home, but are actively or passively stigmatized when attempting to do so. For all its draconian measures, China is showing them to be effective for the time being. In the same way, we could've rid ourselves of many pests, plagues and illnesses ages ago which a simple "get your immune system up bro" couldn't deal with.

bilekas 7y ago

> people should focus on improving their immune system Okay, but for those who cant, underlining conditions etc, what do you suggest ? This is the world we live in, and that kind of build up you're talking about that would fight off all these strains of virus' would take generations of active measures. In the meantime, I don't think it's a bad idea to develop vaccines and shots which will aid our immune system. Our body uses the memory DNA (or memory cells - Not a doctor) after getting chicken-pox so that we (usually) don't get it again. But the COVID strains vary so much it's a little pie-in-the sky right now to imagine naturally fighting all of them. Our best defense is our ability to maintain good hygiene in this generation. We know all about how these things spread, and that should be the primary focus for the every day to day person.

LinuxBender 7y ago
Everyone will eventually get one of the mutations. [1] Maybe a vaccine will cover all of them some day. In the mean time, everyone, especially those with pre-exisiting conditions should be focusing on removing burdens from their immune system (sugar, carbs, anything that spikes insulin), getting a LOT of sleep, and ensuring they are not deficient in D3, Zinc, L-Glutamine, Magnesium, well, all the essential minerals, vitamins and enzymes. I have not had a vaccine since the 1990's and I have only noticeably had the flu twice (h1n1, h3n2) and even then it just made me gassy. I went home as a courtesy to my coworkers. I have not had a cold in 15 years. [1] - https://nextstrain.org/ncov https://nextstrain.org/ncov