1) Get a mouse that's flexible enough to use with either your left or right hand. It might feel weird at first, but switching sides every hour will reduce a lot

1) Get a mouse that's flexible enough to use with either your left or right hand. It might feel weird at first, but switching sides every hour will reduce a lot the pain. Takes a bit to get used to but you'll eventually adjust. 2) Try to use the keyboard as much as possible for everything. Go into your Keyboard & Mouse settings and enable full keyboard access (or ^fn F7 to toggle on/off) 3) Use either Firefox/Camino for you main browsing because you can enable "find as you type" which you can use to navigate the links on a web page. 4) Take regular/breaks. I use http://tech.inhelsinki.nl/antirsi/ http://tech.inhelsinki.nl/antirsi/ to remind me at set intervals. 5) Exercise regularly (running, walking, golf, something to get you away from you computer). 6) Meditate, relax, listen to music. Whenever I feel like I'm tired or overstressed, I listen to this for about 20 minutes. I'll feel refreshed and much more focused. http://www.pzizz.com/ http://www.pzizz.com/ (Energizer track)