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I am not a native speaker, but the conclusion of the article seems to me to state two different and contradictory opinions: Our findings indicated that no dire
by JPLeRouzic 7y ago
I am not a native speaker, but the conclusion of the article seems to me to state two different and contradictory opinions:
Our findings indicated that no direct evidence was identified genetically supporting the existence of coronavirus S-protein binding-resistant ACE2 mutants in different populations
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The East Asian populations have much higher AFs in the eQTL variants associated with higher ACE2 expression in tissues (Fig. 1c), which may suggest different susceptibility or response to 2019-nCoV/SARS-CoV-2 from different populations under the similar conditions.
- martingoodson 7y agoThe first statement refers to mutations in the coding sequence of the gene (which affect the protein sequence). The second is about expression levels (how much protein is produced).