The last time so checked, I could not find anything preventing the use of Lora in space (if you are operating in the UK). However, the frequencies you can use a

The last time so checked, I could not find anything preventing the use of Lora in space (if you are operating in the UK). However, the frequencies you can use are different over different territories so it is up to your satellite to use the correct ones depending on where it is and what it is pointing at.