4 ms·

Woman took 550x the usual dose of LSD, with surprisingly positive consequences

49 points by daegloe 7y ago

birdyrooster 7y ago
If our employers and industry talking heads are interested in creating a new technical revolution in Silicon Valley or elsewhere, they would lobby to change the scheduling laws of LSD and other psychedelics. We will use our access to LSD to live more healthfully and creatively than ever.
- vb6sp6 7y ago
  > If our employers and industry talking heads are interested in creating a new technical revolution in Silicon Valley or elsewhere They are interested in money and power. The tech is simply a tool to get those things
deleted 7y ago
[deleted]
spamcast 7y ago
tired: microdosing wired: evidence based psychedelic pharmacotherapy inspired: macrodosing
- eurasiantiger 7y ago
  Or as they used to say... Turn on Tune in Drop out
- kortex 7y ago
  This seems against the typical HN tone, so expect some tightpants to downvote this, but it gave me a hearty chuckle. Much appreciated.
skissane 7y ago
Case report from 1974: "Coma, Hyperthermia and Bleeding Associated with Massive LSD Overdose: A Report of Eight Cases" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1129381/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1129381/
- craftinator 7y ago
  I would be skeptical of the objectivity of this given the time period, as well as the quality of the LSD. Mid 70s had a lot of homebrew drugs going on, and cutting and mixing were just ramping up.
  - wahern 7y ago
    In addition to testing of their stomach contents, urine, and blood (pp184-185), "A white flaky material (208mg) was confiscated by police and identified as the large quantity of powder used at the party. Analysis by thin layer chromatography, fluorescent analysis, mass spectrography and the melting point and mix melting point identified this substance as almost pure (80 to 90 percent) D-lysergic acid diethylamide tartrate." p185.
HoveringOrb 7y ago
>The woman blacked out and vomited frequently for the next 12 hours Hey, I love LSD as much as the next guy, but that sounds like a dangerous combination of status effects.
- hcarvalhoalves 7y ago
  It always feels great when you don’t die. Could probably replace the LSD with anything that makes you go thru an ordeal without lasting damage. You’ll feel great due to the endorphins alone.
- Fricken 7y ago
  Sounds similar to what people endure when they take ayahuasca.
- meowface 7y ago
  Still sounds not too bad when you consider it's a 5,500 mcg LSD dose.
eindiran 7y ago
Keeping LSD around in powder form, especially not clearly labelled is so irresponsible. There are all these mythical stories floating around of people 'thumbprinting' LSD (effectively pouring dozens or hundreds of milligrams of LSD onto a surface, licking your finger, smearing your finger in the pile of LSD, and then pressing your thumb into your mouth - dosing yourself with many hundreds or thousands of times the conventional dose of LSD), usually in the folklore surrounding the people that followed the Grateful Dead. I'm not sure how many of these stories are real, but they are certainly interesting. Also, FTA: "mescaline (the psychoactive compounds in magic mushroom)". Come on CNN, spending five seconds to search for mescaline on Wikipedia will show you that that isn't true.
HiLoRanger 7y ago
No, LSD doesn't cure bipolar disorder. I have bipolar disorder. I have taken LSD. It didn't cure me. I have met other bipolar people in treatment. A lot of them have taken LSD, some of them in huge amounts (e.g. while manic, when "no" is temporarily removed from your vocabulary) and as far as I can tell, the ones who have taken the most acid have the worst problems: more frequent cycling, higher highs, lower lows, more agitated depression (very bad because it can cause suicide), and more frequent loss of contact with reality. And the article is pretty insensitive about bipolar disorder in general. It says literally nothing about what it's like to have it, or how to cope with it, or that you can lead a relatively normal life in spite of it. It certainly says nothing about the good parts to having bipolar disorder, that the disease imparts certain talents, and that some bipolar people would opt not to cure themselves if they had the choice. In the article bipolar disorder is just this generic bad thing that sets the stage for the healing power of acid. Frankly, my life, and the lives of the other people I've met, are just a lot more interesting than that.
- ta999999171 7y ago
  Did you use a test kit?
teslaberry 7y ago
why not try 10,000,000 times the usual dose. let's keep going!

49 points by daegloe 7y ago

If our employers and industry talking heads are interested in creating a new technical revolution in Silicon Valley or elsewhere, they would lobby to change the scheduling laws of LSD and other psychedelics. We will use our access to LSD to live more healthfully and creatively than ever.

vb6sp6 7y ago
> If our employers and industry talking heads are interested in creating a new technical revolution in Silicon Valley or elsewhere They are interested in money and power. The tech is simply a tool to get those things

deleted 7y ago

[deleted]

spamcast 7y ago

tired: microdosing wired: evidence based psychedelic pharmacotherapy inspired: macrodosing

eurasiantiger 7y ago
Or as they used to say... Turn on Tune in Drop out
kortex 7y ago
This seems against the typical HN tone, so expect some tightpants to downvote this, but it gave me a hearty chuckle. Much appreciated.

skissane 7y ago

Case report from 1974: "Coma, Hyperthermia and Bleeding Associated with Massive LSD Overdose: A Report of Eight Cases" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1129381/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1129381/

craftinator 7y ago
I would be skeptical of the objectivity of this given the time period, as well as the quality of the LSD. Mid 70s had a lot of homebrew drugs going on, and cutting and mixing were just ramping up.
- wahern 7y ago
  In addition to testing of their stomach contents, urine, and blood (pp184-185), "A white flaky material (208mg) was confiscated by police and identified as the large quantity of powder used at the party. Analysis by thin layer chromatography, fluorescent analysis, mass spectrography and the melting point and mix melting point identified this substance as almost pure (80 to 90 percent) D-lysergic acid diethylamide tartrate." p185.

HoveringOrb 7y ago

>The woman blacked out and vomited frequently for the next 12 hours Hey, I love LSD as much as the next guy, but that sounds like a dangerous combination of status effects.

hcarvalhoalves 7y ago
It always feels great when you don’t die. Could probably replace the LSD with anything that makes you go thru an ordeal without lasting damage. You’ll feel great due to the endorphins alone.
Fricken 7y ago
Sounds similar to what people endure when they take ayahuasca.
meowface 7y ago
Still sounds not too bad when you consider it's a 5,500 mcg LSD dose.

eindiran 7y ago

Keeping LSD around in powder form, especially not clearly labelled is so irresponsible. There are all these mythical stories floating around of people 'thumbprinting' LSD (effectively pouring dozens or hundreds of milligrams of LSD onto a surface, licking your finger, smearing your finger in the pile of LSD, and then pressing your thumb into your mouth - dosing yourself with many hundreds or thousands of times the conventional dose of LSD), usually in the folklore surrounding the people that followed the Grateful Dead. I'm not sure how many of these stories are real, but they are certainly interesting. Also, FTA: "mescaline (the psychoactive compounds in magic mushroom)". Come on CNN, spending five seconds to search for mescaline on Wikipedia will show you that that isn't true.

HiLoRanger 7y ago

No, LSD doesn't cure bipolar disorder. I have bipolar disorder. I have taken LSD. It didn't cure me. I have met other bipolar people in treatment. A lot of them have taken LSD, some of them in huge amounts (e.g. while manic, when "no" is temporarily removed from your vocabulary) and as far as I can tell, the ones who have taken the most acid have the worst problems: more frequent cycling, higher highs, lower lows, more agitated depression (very bad because it can cause suicide), and more frequent loss of contact with reality. And the article is pretty insensitive about bipolar disorder in general. It says literally nothing about what it's like to have it, or how to cope with it, or that you can lead a relatively normal life in spite of it. It certainly says nothing about the good parts to having bipolar disorder, that the disease imparts certain talents, and that some bipolar people would opt not to cure themselves if they had the choice. In the article bipolar disorder is just this generic bad thing that sets the stage for the healing power of acid. Frankly, my life, and the lives of the other people I've met, are just a lot more interesting than that.

ta999999171 7y ago
Did you use a test kit?

teslaberry 7y ago

why not try 10,000,000 times the usual dose. let's keep going!