This will always be an issue unless you use a distributed/mirror/farm architecture with more than one data-centre. Most decent data centres are highly resilien

This will always be an issue unless you use a distributed/mirror/farm architecture with more than one data-centre. Most decent data centres are highly resilient and reliable (i.e. cheap solutions are not always worth the headaches if you run important apps/services) but, regardless, if you put all your eggs in one basket there is not much you can do if the basket drops.