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Definitely. The State Department has a set of pages noting that mosquitoes with malaria have developed chloroquine resistance in every country with malaria, and

Definitely. The State Department has a set of pages noting that mosquitoes with malaria have developed chloroquine resistance in every country with malaria, and recommends other drugs instead. The main manufacturer of chloroquine, Bayer, stopped producing it a while back. Not sure who if anyone even makes it these days. I'm assuming the Chinese trials are using some old stock.

fspeech 7y ago
They restarted old lines. These are not terribly hard to make. There was just no demand.
- droithomme 7y ago
  Do you know they (the Chinese presumably, if not who) restarted old lines, or are you guessing that you think they did? It would be great if chloroquinine is back in production.
  - fspeech 7y ago
    It was reported in the news. Also Bayer donated a bunch to China from their stock in Pakistan. It's possible that HCQ, which is widely available, has similar effectiveness.
    - droithomme 7y ago
      Thanks, that enabled me to find the 1/28 donation news: https://www.marketscreener.com/BAYER-AG-436063/news/Bayer-to-Donate-Medicines-to-Treat-Coronavirus-29900181/ https://www.marketscreener.com/BAYER-AG-436063/news/Bayer-to... It mentions "antibiotics and analgesics" but not quinine, but I'll accept you've seen a more detailed report. I was unable to find a report saying that Chloroquine lines have started back up. By HCQ do you mean Quinine Hydrochloride as is found in Tonic Water? Do you have any links to studies showing it has "similar effectiveness" as Chloroquine in treatment? I'm taking Quinine Hydrochloride at present since it's harmless and available, but have not seen any studies about it specifically regarding the new virus.
      - fspeech 7y ago
        HCQ is hydroxychloroquine, an antimalarial that is still widely available because it is used for autoimmune diseases. It is a prescription only drug. The antiviral property is described in this Lancet article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(03)00806-5/fulltext https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
        droithomme 7y ago
        Thanks!
  - tim333 7y ago
    Cranking away: https://www.shine.cn/biz/economy/2002202403/ https://www.shine.cn/biz/economy/2002202403/ >Multinational and local drugmakers are speeding up manufacturing and supply of chloroquine phosphate after the anti-malarial drug was included in the latest version of treatment guidelines for novel coronavirus pneumonia by the National Health Commission. >China Resources Group now has inventory of more than 325,000 boxes and is preparing for further demand
tim333 7y ago
It is made and used in some countries. Belize for example has non resistant malaria.

fspeech 7y ago

They restarted old lines. These are not terribly hard to make. There was just no demand.

droithomme 7y ago
Do you know they (the Chinese presumably, if not who) restarted old lines, or are you guessing that you think they did? It would be great if chloroquinine is back in production.
- fspeech 7y ago
  It was reported in the news. Also Bayer donated a bunch to China from their stock in Pakistan. It's possible that HCQ, which is widely available, has similar effectiveness.
  - droithomme 7y ago
    Thanks, that enabled me to find the 1/28 donation news: https://www.marketscreener.com/BAYER-AG-436063/news/Bayer-to-Donate-Medicines-to-Treat-Coronavirus-29900181/ https://www.marketscreener.com/BAYER-AG-436063/news/Bayer-to... It mentions "antibiotics and analgesics" but not quinine, but I'll accept you've seen a more detailed report. I was unable to find a report saying that Chloroquine lines have started back up. By HCQ do you mean Quinine Hydrochloride as is found in Tonic Water? Do you have any links to studies showing it has "similar effectiveness" as Chloroquine in treatment? I'm taking Quinine Hydrochloride at present since it's harmless and available, but have not seen any studies about it specifically regarding the new virus.
    - fspeech 7y ago
      HCQ is hydroxychloroquine, an antimalarial that is still widely available because it is used for autoimmune diseases. It is a prescription only drug. The antiviral property is described in this Lancet article: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(03)00806-5/fulltext https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
      - droithomme 7y ago
        Thanks!
- tim333 7y ago
  Cranking away: https://www.shine.cn/biz/economy/2002202403/ https://www.shine.cn/biz/economy/2002202403/ >Multinational and local drugmakers are speeding up manufacturing and supply of chloroquine phosphate after the anti-malarial drug was included in the latest version of treatment guidelines for novel coronavirus pneumonia by the National Health Commission. >China Resources Group now has inventory of more than 325,000 boxes and is preparing for further demand

tim333 7y ago

It is made and used in some countries. Belize for example has non resistant malaria.