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Industrial chloroquine manufacturing was developed in the 1940s. There is an extensive description in this 1949 article from Industrial and Engineering Chemistr
by philipkglass 7y ago
Industrial chloroquine manufacturing was developed in the 1940s. There is an extensive description in this 1949 article from Industrial and Engineering Chemistry:
"Chloroquine Manufacture"
https://sci-hub.tw/10.1021/ie50472a002 https://sci-hub.tw/10.1021/ie50472a002
I mention chloroquine specifically because
a) It looks like it was effective at a lower concentration than remdesivir, according to this Nature article.
b) It's a simpler molecule. High volume production started back during World War II.