There's plenty of cases where inflammation is not helpful at all, such as arthritis and psoriasis. When the body is attacking itself in an immune disorder, ther

There's plenty of cases where inflammation is not helpful at all, such as arthritis and psoriasis. When the body is attacking itself in an immune disorder, there's really no down side to preventing the body from attacking itself. Unfortunately, such disorders become more and more common the older you get, so you can think of it as the immune system accidentally triggering rather than it triggering too much on some particular thing. It's true, though, that for really severe inflammation disorders that doctors start prescribing systemic immunosuppressants, which then result in the patient getting real illnesses more often. Often the patient has such a bad condition at that point - my psoriasis leads to skin flaking off in bloody patches and smearing blood on the things I touch and my hands feeling like sand paper to other people, for example - that they prefer this overall. Even the localized topical immunosuppressants like hydrocortisone cream have negative side effects like skin thinning, but I think everyone using those agrees it's better than the extra inflammation.