4 ms·

Covid-19 Vaccine Shipped, and Drug Trials Start

4 points by thrusong 7y ago

mrfusion 7y ago
Anyone up for explaining how this works? The immune cells pick up mRNA in blood plasma and actually “run” it and produce proteins from it? I’ve never heard that. That’s like a computer crawling the internet and running any executables it finds, no?
- rolph 7y ago
  there is a firewall in there with regard to your analogy anything floating about that is not loggedin is processed as malware the sequence of data must be read in order to get the structural motif a set of antibodies that bind to the structure are then selected and used to label the malware for low level sector deletion
  - rolph 7y ago
    oBTW in order to refine your model, "blood" plasma actually extends beyond the blood stream and into the extracellular matrix so the patrol for malware [antigens] [foriegn bodies] will occur there as well its kind of technical if your not strong on biology but check this out from wikipedia: https://en.wikipedia.org/wiki/Immune_system#Adaptive_immune_system https://en.wikipedia.org/wiki/Immune_system#Adaptive_immune_...
  - mrfusion 7y ago
    That’s kind of making sense. What’s this process called so I can read more? Just the rna part, I feel familiar with the general workings. So immune cells can make antibodies from foreign proteins or pieces of proteins or they can actually run rna and make foreign proteins.
    - rolph 7y ago
      no immune cells dont run foreign rna to translate into protiens they detect features of the rna and then select a set of antibodies that will interact this is like reading the header of a file and determining that it has properties of hostile code those properties will then be used to find a response that worked to purge the code at no time is the code executed during immune response, when the viral rna executes that means it has invaded the cell and established functionality == infection the process involving decoding rna is part of a multi step process ill start with DNA the process of reading DNA and making messengerRNA is called Transcription mRNA is then subject to Translation thus producing protiens the RNA has to have access to the Ribosomes in order to be translated ribosomes are a factory that uses the RNA as a combination bluprint/template for production of protiens in a final functional state https://en.wikipedia.org/wiki/Translation_(biology) https://en.wikipedia.org/wiki/Translation_(biology) any mRNA somehow getting into any [Eukaryotic] cell must run a gauntlet against the normal flow of traffic so must be adorned with the right tags and labels this is the obstacle course involved: https://en.wikipedia.org/wiki/MRNA_surveillance https://en.wikipedia.org/wiki/MRNA_surveillance

4 points by thrusong 7y ago

Anyone up for explaining how this works? The immune cells pick up mRNA in blood plasma and actually “run” it and produce proteins from it? I’ve never heard that. That’s like a computer crawling the internet and running any executables it finds, no?

rolph 7y ago
there is a firewall in there with regard to your analogy anything floating about that is not loggedin is processed as malware the sequence of data must be read in order to get the structural motif a set of antibodies that bind to the structure are then selected and used to label the malware for low level sector deletion
- rolph 7y ago
  oBTW in order to refine your model, "blood" plasma actually extends beyond the blood stream and into the extracellular matrix so the patrol for malware [antigens] [foriegn bodies] will occur there as well its kind of technical if your not strong on biology but check this out from wikipedia: https://en.wikipedia.org/wiki/Immune_system#Adaptive_immune_system https://en.wikipedia.org/wiki/Immune_system#Adaptive_immune_...
- mrfusion 7y ago
  That’s kind of making sense. What’s this process called so I can read more? Just the rna part, I feel familiar with the general workings. So immune cells can make antibodies from foreign proteins or pieces of proteins or they can actually run rna and make foreign proteins.
  - rolph 7y ago
    no immune cells dont run foreign rna to translate into protiens they detect features of the rna and then select a set of antibodies that will interact this is like reading the header of a file and determining that it has properties of hostile code those properties will then be used to find a response that worked to purge the code at no time is the code executed during immune response, when the viral rna executes that means it has invaded the cell and established functionality == infection the process involving decoding rna is part of a multi step process ill start with DNA the process of reading DNA and making messengerRNA is called Transcription mRNA is then subject to Translation thus producing protiens the RNA has to have access to the Ribosomes in order to be translated ribosomes are a factory that uses the RNA as a combination bluprint/template for production of protiens in a final functional state https://en.wikipedia.org/wiki/Translation_(biology) https://en.wikipedia.org/wiki/Translation_(biology) any mRNA somehow getting into any [Eukaryotic] cell must run a gauntlet against the normal flow of traffic so must be adorned with the right tags and labels this is the obstacle course involved: https://en.wikipedia.org/wiki/MRNA_surveillance https://en.wikipedia.org/wiki/MRNA_surveillance