> The most lethal way tobacco smoking impacts health is through carcinogenic by-products created from metabolizing said tobacco. Maybe, we're misunderstanding

> The most lethal way tobacco smoking impacts health is through carcinogenic by-products created from metabolizing said tobacco. Maybe, we're misunderstanding each other. But all those compounds you listed are directly present in smoke itself. I.e. they're not metabolic byproducts. In fact they're not even related to tobacco specifically. (With the major exception of N-nitrosamine). Cannabis smoke (gram for gram) contains equivalent of higher levels of PAH, benzene, 1,3-butadiene, aldehyde, and aromatic amines.[1] These are all pretty much universal byproducts of burning any type of dried plant material, and the same reason that exposures are similar for wood-burning fireplaces.[2] [1] https://pubs.acs.org/doi/full/10.1021/tx700275p https://pubs.acs.org/doi/full/10.1021/tx700275p [2] https://www.epa.gov/burnwise/wood-smoke-and-your-health https://www.epa.gov/burnwise/wood-smoke-and-your-health