3 ms·
I’m usually also skeptical of getting excited about successful animal trials for new medications, but with this I’m actually leaning more on the side of optimis
by headmelted 7y ago
I’m usually also skeptical of getting excited about successful animal trials for new medications, but with this I’m actually leaning more on the side of optimism.
With cancer treatments and antivirals in mice, we’re not so much targeting the pathogen as targeting the host immune system in the hopes it ends up nerfing the intended target (tumor/virus/whatever).
Given that the compound seems effective against C. Difficile (even if it’s in mice), I’d expect it to work elsewhere.
Of course, I’m not a doctor and have no idea what I’m talking about so grain of salt required.
- m3kw9 7y agoProblem with many of these molecules that are found to work in mice, when put in human which is considerably more complex, say it goes thru the liver, the liver may break down most of it when circulating the blood stream. So now the drug needs to also resist that type of break down. Now multiply that by 10 to 100 of other types of reactions your body can generate from this.
- pacman128 7y agoAre humans more complex than mice or just different? I've always assumed the latter, but I'm in no way an expert.
- whatshisface 7y agoThe mouse genome is about 14% shorter than the human genome, although that could mean a lot or a little depending on certain other factors.
- sjg007 7y agoWell c diff is in the gut so it’ll work there probably.