It sucks, but I've done it and do it. Unfortunately sometimes you just have to. But these are maybe around 10h max flights - given the range of ~4000-4500 mil

It sucks, but I've done it and do it. Unfortunately sometimes you just have to. But these are maybe around 10h max flights - given the range of ~4000-4500 miles. So you're still on a plane for ~5 hours. But you still have the same issues with time zones. If you need a lot of time to adjust to a new time zone, you were always flying in way earlier - so whether your flight is 5 hours or 10 doesn't really matter much. You were never going to red-eye in for a morning meeting in London or Paris either way.