There are (IMHO) two scenarios where this doesn't matter: If you're writing a web service then the multi threading (processing) is done by the front end ie Ngin

There are (IMHO) two scenarios where this doesn't matter: If you're writing a web service then the multi threading (processing) is done by the front end ie Nginx; and for 'scientific' or similar computationally expensive stuff Python is turning into a scripting layer over C libraries. Have a look at numpy to see what I mean.