"For example: there has yet to be a breakthrough in the last 50 years that could even come close the impact of antibiotics and nobody has set foot on the moon i

"For example: there has yet to be a breakthrough in the last 50 years that could even come close the impact of antibiotics and nobody has set foot on the moon in five decades. But if you told someone that in the late 60s, I think they wouldn't believe it." This shouldn't be that surprising when you think about the situation just a little bit. Antibiotics are important because they cover a wide variety of diseases that formerly were untreatable. This is the case because they all have the same cause: bacteria. Other classes of disease, such as cancer, aren't so simple. There isn't a single treatment that can reliably cure all forms of cancer and theoretically there really can't be. It's just a fundamentally harder problem. There's a lot a low hanging fruit in basic discoveries but then we hit a wall when we attempt to apply them to more difficult problems. Back in the 50's (I think) there was a fascination with the possibility of weather prediction. It seemed reasonable at the time that because the weather was ultimately a deterministic system we could predict it months in advance just by figuring out the physics and running the correct calculations. Then we discovered chaos theory and "sensitive dependence on initial conditions" and we realized that weather prediction was a fundamentally much harder problem than we could have predicted. We simply can't ever measure the atmosphere accurately enough to accurately predict the weather more than a few weeks in advance and even then we have to take a probabilistic approach. There's a similar deal with fast planes as mentioned in the article. Back in the 60s and 70s all the big aerospace engineers wanted to be working on supersonic airliners like the Concord. Decades later, that effort seems to have been a waste of time. It turns out that the physics of supersonic flight present challenges and the economics of intercontinental travel don't really cover those challenges. The changes that have been made to airliners over the last few decades have been instead in terms of efficiency and safety. Even in the military sector, which can throw tons of money at pie-in-the-sky ideas has run into this. The most populous strategic bomber in the US Airforce is still the B-52 which was introduced in the mid 50s. We do have more advanced weapons, but we can't afford them, and we can't afford them precisely because of the changes that make them more advanced. If someone in the late 60s wouldn't believe that we'd not repeat the success of antibiotics or return to the moon, it would have been because of misconceptions about the nature of the problems involved in the 60s rather than because of some form of decadence that settled in after the fact.