My guess is that this would vary much between types of occupations. I can see that occupations involving highly repetitive actions (assembly line work etc) migh

My guess is that this would vary much between types of occupations. I can see that occupations involving highly repetitive actions (assembly line work etc) might cause problems. Many more varied, often outdoor, manual jobs strike me as putting a human fairly close to the kinds of activities for which our body evolved. Anecdotally, every single fit, strong & able old person I've known has been a manual worker. Case in point: 90 year lifelong builder currently doing roofing work. 87 year old (my sailing instructor!) currently running (on the ground) his tree surgery business. Most lifelong office workers I know are barrel shaped and essentially disabled by their 50s. The stats might be interesting, though I suspect they'd be pretty complex, different by region & nation, and highly confounded (by class, lifestyle, etc).