I don't believe Derek is denying the role of amyloid formation in Alzheimer's here. Just questioning the efficacy of this particular therapeutic hypothesis. Not

I don't believe Derek is denying the role of amyloid formation in Alzheimer's here. Just questioning the efficacy of this particular therapeutic hypothesis. Note that the therapeutic hypothesis and mechanistic hypothesis can co-exist and be slightly disjoint due to the lack of a deeper understanding of the disease. That's how I interpret this post, at least.