It's not necessarily pathogens only but it can also be commensal dysbiosis. See the discussion linked by the parent comment or my other comment here. We should

It's not necessarily pathogens only but it can also be commensal dysbiosis. See the discussion linked by the parent comment or my other comment here. We should start thinking about all diseases that involve the HLA gene and dysfunctional immune responses as autoimmunity. Not just the obvious ones. Hence the question is simply why is the immune system misclassifying our own tissues? It's a CS / information theory problem.