Astronaut Garrett Reisman on Joe Rogan show said something that resonated with me, we have plenty of experience with 1G of gravity and enough experience with 0G

Astronaut Garrett Reisman on Joe Rogan show said something that resonated with me, we have plenty of experience with 1G of gravity and enough experience with 0G. They know the physical effects of both of those. What they do not know is effect of 0.2G or 0.5G in long term. Whether effect is linear or is it a curve. Etc. That's just for exploring long term space habitation. Another major reason to do it would be a potential mining/fueling base on the moon. Cost of any launch from Earth is quite prohibitive due to Earth gravity, Moon has gravity that is 6 times less powerful so if we managed to mine ice/hydrogen/oxygen from the surface of the moon it could be used to refuel rockets in space for missions to the rest of the solar system.