It really depends on what it is you're shipping. Once a startup hits some level of maturity, it's unacceptable to be shipping something significant on the week

It really depends on what it is you're shipping. Once a startup hits some level of maturity, it's unacceptable to be shipping something significant on the weekend (or whenever people aren't around to respond to an issue). Probably post product-market fit, maybe Series B. I guess it also matters how much your company values work-life balance.