4 ms·
> In theory, it is possible that because a lot of people smoke or vape in China, that they have reduce lung functionality. Smokers have more ACE2 receptors, wh
by Alex3917 7y ago
> In theory, it is possible that because a lot of people smoke or vape in China, that they have reduce lung functionality.
Smokers have more ACE2 receptors, which is what this virus targets. As they get closer to death and their blood oxygen levels drop, I have no doubt that having damaged lungs doesn't help their chances, but the reason smokers are more at risk goes beyond this.
- eindiran 7y agoSource? Because this suggests the opposite: https://journals.physiology.org/doi/abs/10.1152/ajpregu.00099.2018 https://journals.physiology.org/doi/abs/10.1152/ajpregu.0009... "The literature presented in this review strongly suggests that nicotine alters the homeostasis of the RAS by ... downregulating the compensatory ACE2/ANG-(1–7)/Mas receptor axis." "In primary cultures of neurons and glial cells isolated from brainstem and hypothalamus of 1-day-old rats, nicotine treatment resulted in increased expression of AT 1 R but decreased expression of ACE2."