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Studies from patients who died from SARS coronavirus showed the virus caused damage to not only the lungs, but also other organs in the body. Early research sug

by keanzu 7y ago

Studies from patients who died from SARS coronavirus showed the virus caused damage to not only the lungs, but also other organs in the body. Early research suggests the Wuhan coronavirus can also damage other organs, including the kidneys. The Wuhan coronavirus appears to cause pneumonia in two ways: when the virus takes hold in the lungs, and through secondary bacterial infections, however, the first way appears to be more common. Although it can be difficult to determine whether organ damage from the Wuhan coronavirus is a result of direct viral infection or indirect “collateral damage” from the immune system, initial reports suggested around 11% of people severely ill with the Wuhan coronavirus experienced sepsis with multi-organ failure. https://theconversation.com/how-does-the-wuhan-coronavirus-cause-severe-illness-130864 https://theconversation.com/how-does-the-wuhan-coronavirus-c... I am not a medical practitioner nor researcher and have no understanding of the virus. I make no representation as to the veracity of this source lacking the means to independently verify it.

sillysaurusx 7y ago
Fascinating. The immune response seems to cause harm, so the logical conclusion might be to try to suppress it somehow. But the article points out that 100 attempts at dampening immune response have all failed: https://www.ncbi.nlm.nih.gov/m/pubmed/24581450/ https://www.ncbi.nlm.nih.gov/m/pubmed/24581450/
- bgee 7y ago
  When battling with SARS, large dose of steroids was used as part of the treatment to suppress immune system [0]. But there are many side-effects (e.g. lots of SARS survivors in China need hip replacement [1]). [0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420028/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420028/ [1]: https://www.scmp.com/article/433797/28-sars-survivors-have-bone-disease https://www.scmp.com/article/433797/28-sars-survivors-have-b...
jnwatson 7y ago
It is hard to square 11% “sepsis with multiple organ failure” with only 2% reported fatality rate. Somebody isn’t telling the truth, and I’d bet it is the Chinese government.
- RcouF1uZ4gsC 7y ago
  > Of the first 99 people with severe infection, three-quarters had pneumonia involving both lungs. Around 14% appeared to have lung damage caused by the immune system, while 11% suffered from multi-organ system failure, or sepsis. The 11% with multiple organ failure is referring to the first 99 people with severe infection. The 2% reported fatality rate is for everyone that acquires the virus.
  - koheripbal 7y ago
    No - 2% is only for those sick enough to have the test administered. Many are not even being checked because their symptoms don't warrant hospitalization.
- keanzu 7y ago
  "around 11% of people severely ill" Many of the infected are not "severely ill".

by keanzu 7y ago

sillysaurusx 7y ago

Fascinating. The immune response seems to cause harm, so the logical conclusion might be to try to suppress it somehow. But the article points out that 100 attempts at dampening immune response have all failed: https://www.ncbi.nlm.nih.gov/m/pubmed/24581450/ https://www.ncbi.nlm.nih.gov/m/pubmed/24581450/

bgee 7y ago
When battling with SARS, large dose of steroids was used as part of the treatment to suppress immune system [0]. But there are many side-effects (e.g. lots of SARS survivors in China need hip replacement [1]). [0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420028/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420028/ [1]: https://www.scmp.com/article/433797/28-sars-survivors-have-bone-disease https://www.scmp.com/article/433797/28-sars-survivors-have-b...

jnwatson 7y ago

It is hard to square 11% “sepsis with multiple organ failure” with only 2% reported fatality rate. Somebody isn’t telling the truth, and I’d bet it is the Chinese government.

RcouF1uZ4gsC 7y ago
> Of the first 99 people with severe infection, three-quarters had pneumonia involving both lungs. Around 14% appeared to have lung damage caused by the immune system, while 11% suffered from multi-organ system failure, or sepsis. The 11% with multiple organ failure is referring to the first 99 people with severe infection. The 2% reported fatality rate is for everyone that acquires the virus.
- koheripbal 7y ago
  No - 2% is only for those sick enough to have the test administered. Many are not even being checked because their symptoms don't warrant hospitalization.
keanzu 7y ago
"around 11% of people severely ill" Many of the infected are not "severely ill".