I personally find that screen tries to do less, and therefore, gets in my way less. Also, emacs-style keybindings fit better with the general interaction model

I personally find that screen tries to do less, and therefore, gets in my way less. Also, emacs-style keybindings fit better with the general interaction model of the shell, which also uses emacs-style keybindings. I know that one can switch to vim-style keybindings in the shell, but they have never felt as "comfortable" (and I use vim as my daily driver). Last but not least, the default keybinding for splitting in tmux (C-b ") is just awkward. Screen has way better defaults.