5 ms·
You have some time now to find those opposing drug study citations. Your claims interest me and I'd like to subscribe to your newsletter, but the rubber will st
by msg 18y ago
You have some time now to find those opposing drug study citations. Your claims interest me and I'd like to subscribe to your newsletter, but the rubber will start hitting the road for me if this conversation progresses from accusations to evidence.
Here's an example of the kind of thing that interests me: a recent meta-study of FDA trials of SSRIs (antidepressants) showed little to no benefit over placebo, below statistical significance in some important cases. So there's a fair chance that most people shouldn't get SSRIs because they just don't work.
"Drug–placebo differences in antidepressant efficacy increase as a function of baseline severity, but are relatively small even for severely depressed patients. The relationship between initial severity and antidepressant efficacy is attributable to decreased responsiveness to placebo among very severely depressed patients, rather than to increased responsiveness to medication."
Read it here.
http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0050045&ct=1 http://medicine.plosjournals.org/perlserv/?request=get-docum...