7 ms·

Am I wrong to find it concerning that Africa and South America has yet to report a single case?

by yummybear 7y ago

TurkishPoptart 7y ago
You are not wrong to find this concerning.
- fiftyfifty 7y ago
  Especially given China's growing presence in Africa, there has to be quite a bit of travel between Africa and China.
  - wh1t3n01s3 7y ago
    They probably have no way to test it. Also -very maybe- the (rich) chinese are preparing their future secret extractions
cuttlebit 7y ago
Because they likely don’t have enough test kits yet.
mikhailfranco 7y ago
2019-nCoV targets ACE2 receptor cells in the lung. Current estimated death rate is 15% (based on now slightly out-of-date Lancet articles). Asian men are the most susceptible group. Male / female infection rate currently about 3:1 (but based on low statistics). Ratio of ACE2 cells in Asian men to Asian women is about 4:1. Ratio of ACE2 cells in Asian men compared to whites or African-Americans is 5:1. https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1.full https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1.... See some criticisms of the methods and results in the comments. Interesting correlation of ACE2 to stress and high blood-pressure, so could be strongly affected by some treatments for hypertension. It is just about possible, in some qualitative hand-waving way, that reducing susceptibility by 80% could drop R0 from 5 to 1, hence reduce the threat of an epidemic in other regions.
- yummybear 7y ago
  That's pretty interesting.
- romanhotsiy 7y ago
  > We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area. the only Asian donor, n=1. It's too bold to claim that Asian men are the most susceptible group.

Am I wrong to find it concerning that Africa and South America has yet to report a single case?

TurkishPoptart 7y ago

You are not wrong to find this concerning.

fiftyfifty 7y ago
Especially given China's growing presence in Africa, there has to be quite a bit of travel between Africa and China.
- wh1t3n01s3 7y ago
  They probably have no way to test it. Also -very maybe- the (rich) chinese are preparing their future secret extractions

cuttlebit 7y ago

Because they likely don’t have enough test kits yet.

mikhailfranco 7y ago

2019-nCoV targets ACE2 receptor cells in the lung. Current estimated death rate is 15% (based on now slightly out-of-date Lancet articles). Asian men are the most susceptible group. Male / female infection rate currently about 3:1 (but based on low statistics). Ratio of ACE2 cells in Asian men to Asian women is about 4:1. Ratio of ACE2 cells in Asian men compared to whites or African-Americans is 5:1. https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1.full https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1.... See some criticisms of the methods and results in the comments. Interesting correlation of ACE2 to stress and high blood-pressure, so could be strongly affected by some treatments for hypertension. It is just about possible, in some qualitative hand-waving way, that reducing susceptibility by 80% could drop R0 from 5 to 1, hence reduce the threat of an epidemic in other regions.

yummybear 7y ago
That's pretty interesting.
romanhotsiy 7y ago
> We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area. the only Asian donor, n=1. It's too bold to claim that Asian men are the most susceptible group.