> 50mg of 5-Meo-DMT is an absolutely terrible idea. That's what I say. > I'd need a citation, or even an anecdote, to believe that it could be lethal. Somewh

> 50mg of 5-Meo-DMT is an absolutely terrible idea. That's what I say. > I'd need a citation, or even an anecdote, to believe that it could be lethal. Somewhere on Reddit or on actualized.org (the place I've learnt about the substance from in the first place). 20 mg also is the highest dose Psychonautwiki mentions as heavy (which suggests nobody should ever try more). Doses directly above that are not straight lethal but, as far as I know, increase chances of getting a heart attack or stopping breathing to dangerous levels (theoretically, my personal experience doesn't actually include even a minor discomfort or disturbance in the heart rate or respiration despite my heart is very prone to rhythm issues). I would love to try a really heroic dose for sake of having an ultimate transcendence experience but wouldn't do that without supervision of a doctor. Psychonautwiki also mentions the toad venom contains about 10% (15% max) of 5-MeO-DMT so 50 mg of the toad venom corresponds to just 5 mg of pure freebase (which is a toy dose). And it also contains 5-HO-DMT (bufotenin) and 5-MeO-NMT which certainly add their flavour to the experience making it different from pure 5-Meo-DMT.