My vote is for Spyder. It gives you everything you need in a very convenient, Python-centric way. The ability to see and inspect variables (especially lists, di

My vote is for Spyder. It gives you everything you need in a very convenient, Python-centric way. The ability to see and inspect variables (especially lists, dicts, and pandas dataframes) in a grid view is a huge productivity win. I wish they would make the line profiler the default and also have built in support for Jupiter notebooks (these are available through plugins but it’s buggy and bad). Also stability took a big step back in the new version 4. But whenever I try anything else I quickly come back to Spyder.